1990 ~ 2106年世界哮喘发病率和死亡率与PM2.5、臭氧和家庭空气污染关系的生态学研究

IF 0.2 Q4 RESPIRATORY SYSTEM
F. Ahmadi, Z. Fallah, F. Shadmani, Meisam Allahmoradi, Pegah Salahshoor, Sheler Ahmadi, Kamyar Mansori
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引用次数: 0

摘要

哮喘是一种慢性气道疾病,其特征是气道对各种刺激的过度反应。目的探讨1990 - 2016年世界哮喘发病率和死亡率与PM2.5、臭氧和家庭空气污染(HAP)水平的关系。材料和方法本生态研究在194个国家进行。哮喘发病率和死亡率从IHME全球疾病负担数据库中提取。年平均人口加权HAP、PM2.5和臭氧数据来自全球空气状况网站。采用基于模型的聚类方法,利用矩阵变量正态分布的有限混合来识别具有三个空气污染指数值相似模式的国家。聚类数量采用贝叶斯信息准则确定,综合完全似然准则采用R软件。采用随机效应模型,应用SAS软件评价各组哮喘发病率与不同年份的关系。结果根据PM2.5、臭氧和HAP的平均值将国家划分为5类。1990 ~ 2005年发病率呈下降趋势,2011 ~ 2016年呈上升趋势。第三类国家的发病率和死亡率最低。第1类和第2类国家的发病率和死亡率分别最高。发病率和死亡率趋势在聚类1中呈上升趋势,在其他聚类中呈下降趋势。结论根据每组国家哮喘的死亡率和发病率趋势,建议采取有效的国家和国际干预措施来处理这类污染物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship between incidence and mortality of asthma with PM2.5, ozone, and household air pollution from 1990 to 2106 in the world: An ecological study
Background Asthma is a chronic airway disease characterized by an overreaction of the airways to a wide range of stimuli. Objective To determine the relationship between the incidence and mortality rate of asthma and the levels of PM2.5, ozone, and household air pollution (HAP) from 1990 to 2016 in the world. Materials and methods This ecological study was conducted across 194 countries. The asthma incidence and mortality rates were extracted from IHME Global Burden of Disease databases. Data on average annual population-weighted HAP, PM2.5, and ozone were obtained from the State of Global Air website. A model-based clustering with a finite mixture of matrix-variate normal distributions was used to identify countries with a similar pattern of three air pollution index values. The number of clusters was determined by the Bayesian information criterion, and R software was used for integrated completed likelihood criterion. The random-effects model was applied to evaluate the relationship between asthma incidence in groups and different years by using the SAS software. Results The countries were classified into five clusters in terms of the mean of PM2.5, ozone, and HAP. The incidence rates had a decreasing trend during 1990–2005 and an increasing trend during 2011–2016 in the clusters. The lowest incidence and mortality rates were observed for countries of cluster 3. The highest incidence and mortality rates were observed for countries in clusters 1 and 2, respectively. The incidence and mortality ratio trends experienced an increase in cluster 1 and a decrease in other clusters. Conclusions Depending on the mortality and incidence trends of asthma in countries in each cluster, effective national and international intervention measures are recommended to deal with such pollutants.
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来源期刊
自引率
0.00%
发文量
46
审稿时长
22 weeks
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of The Egyptian Journal of Chest Diseases and Tuberculosis aims to publish and inform readers and all chest physicians of the progress in medical research concerning all aspect of chest diseases. Publications include original articles review articles, editorials, case studies and reports which are relevant to chest diseases. The Journal also aims to highlight recent updates in chest medicine. . Articles with clinical interest and implications will be given preference.
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