h-ANN模型:使用组合上下文嵌入的综合结肠镜概念编译

Shorabuddin Syed, Adam Angel, H. Syeda, Carole Jennings, Joseph VanScoy, Mahanazuddin Syed, M. Greer, S. Bhattacharyya, M. Zozus, B. Tharian, F. Prior
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引用次数: 2

摘要

结肠镜检查是一种用于检测结直肠癌的筛查和诊断程序,具有监测和提高腺瘤检出率的特定质量指标。这些质量指标存储在不同的文档中,如结肠镜检查、病理和放射学报告。缺乏整合的标准化文献阻碍了结直肠癌的研究。使用自然语言处理(NLP)和机器学习(ML)技术提取临床概念是人工数据抽象的替代方案。上下文词嵌入模型,如BERT(来自变形金刚的双向编码器表示)和FLAIR,提高了NLP任务的性能。结合多个临床训练的嵌入可以改善单词表示并提高临床NLP系统的性能。本研究的目的是使用连接的临床嵌入从合并结肠镜检查文件中提取全面的临床概念。我们为三种报告类型构建了高质量的注释语料库。BERT和FLAIR嵌入在未标记的结肠镜相关文件上进行训练。我们建立了一个混合人工神经网络(h-ANN)来连接和微调BERT和FLAIR嵌入。为了从三种报告类型中提取感兴趣的概念,从h-ANN中初始化3个模型,并使用带注释的语料库进行微调。模型结肠镜、病理和放射学报告的f1得分分别为91.76%、92.25%和88.55%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The h-ANN Model: Comprehensive Colonoscopy Concept Compilation using Combined Contextual Embeddings
Colonoscopy is a screening and diagnostic procedure for detection of colorectal carcinomas with specific quality metrics that monitor and improve adenoma detection rates. These quality metrics are stored in disparate documents i.e., colonoscopy, pathology, and radiology reports. The lack of integrated standardized documentation is impeding colorectal cancer research. Clinical concept extraction using Natural Language Processing (NLP) and Machine Learning (ML) techniques is an alternative to manual data abstraction. Contextual word embedding models such as BERT (Bidirectional Encoder Representations from Transformers) and FLAIR have enhanced performance of NLP tasks. Combining multiple clinically-trained embeddings can improve word representations and boost the performance of the clinical NLP systems. The objective of this study is to extract comprehensive clinical concepts from the consolidated colonoscopy documents using concatenated clinical embeddings. We built high-quality annotated corpora for three report types. BERT and FLAIR embeddings were trained on unlabeled colonoscopy related documents. We built a hybrid Artificial Neural Network (h-ANN) to concatenate and fine-tune BERT and FLAIR embeddings. To extract concepts of interest from three report types, 3 models were initialized from the h-ANN and fine-tuned using the annotated corpora. The models achieved best F1-scores of 91.76%, 92.25%, and 88.55% for colonoscopy, pathology, and radiology reports respectively.
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