巴勒斯坦未确诊男性血脂异常患病率:一项横断面研究

IF 5.9 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Iyad Ali, Aya Kharma, Malaka Samara, Samar Odeh, N. Jaradat, A. Zaid, Mahdi Al Sayed Ahmad
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A questionnaire was used to collect demographic data about the lifestyle, past medical, and family histories. Serum lipid profile, and fasting blood glucose levels for each participant were measured. Lipoprotein levels were categorized based on the adult treatment panel III criteria. Results The overall prevalence of dyslipidemia among Palestinian men was 66.4%. The most prevalent type of dyslipidemia was hypo HDL (X < 40 mg/dl, 59.3%), followed by hypertriglyceridemia (X ≥ 200 mg/dl, 20%). The prevalence of hyper LDL (X ≥ 160 mg/dl), hypercholesterolemia (X ≥ 240 mg/dl) was 8.5%, and 3.6%, respectively. About 15% of participants had glucose intolerance, and 4.3% had hyperglycemia (undiagnosed). Those with glucose intolerance, 13 (9.2%) have hypo HDL, while 9 (6.42%) have hypertriglyceridemia. On the other hand, out of hyperglycemic patients: 5 (3.5%) had hypo HDL, and 1 (0.7%) had hypertriglyceridemia. 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引用次数: 6

摘要

血脂异常是导致心血管疾病最重要的可改变危险因素。巴勒斯坦的初级卫生保健中心没有为健康人建立血脂异常筛查。我们的研究旨在确定巴勒斯坦未确诊的健康成年男性血脂异常的患病率,以评估对血脂异常进行筛查和预防计划的必要性。材料与方法于2017年8月至2018年2月在巴勒斯坦纳布卢斯市的10所中学开展了一项横断面观察研究。根据抽样计算,该研究包括140名教师。参与者的年龄在24岁到60岁之间。调查问卷用于收集有关生活方式、既往病史和家族史的人口统计数据。测量每位参与者的血清脂质谱和空腹血糖水平。脂蛋白水平根据成人治疗组III标准进行分类。结果巴勒斯坦男性血脂异常总体患病率为66.4%。最常见的血脂异常类型是低HDL (X < 40 mg/dl, 59.3%),其次是高甘油三酯血症(X≥200 mg/dl, 20%)。高LDL (X≥160 mg/dl)和高胆固醇血症(X≥240 mg/dl)的患病率分别为8.5%和3.6%。大约15%的参与者患有葡萄糖耐受不良,4.3%患有高血糖症(未确诊)。葡萄糖耐受不良的患者中,13例(9.2%)有低HDL, 9例(6.42%)有高甘油三酯血症。另一方面,在高血糖患者中:5例(3.5%)患有低HDL, 1例(0.7%)患有高甘油三酯血症。结论:约三分之二未确诊的参与者至少有一种脂质异常。他们都没有意识到自己患有血脂异常。未确诊的血脂异常的患病率高于未确诊的葡萄糖耐受不良和糖尿病的患病率。这表明血脂异常在糖尿病的发生中起着重要作用。因此,为了防止发展为II型糖尿病,我们应该努力管理和治疗这些血脂异常患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Dyslipidemia in Undiagnosed Palestinian Men: A Cross-Sectional Study
Introduction Dyslipidemia is the most important modifiable risk factor that leads to cardiovascular diseases. The screening for dyslipidemia in Palestine is not established in primary health care centers for healthy people. Our study aims to determine the prevalence of dyslipidemia among healthy undiagnosed adult men in Palestine in order to assess the need for screening and preventive programs for dyslipidemia. Materials and Methods A cross-sectional observational study was carried out in 10 secondary schools at Nablus municipality (Palestine) from August 2017 to February 2018. The study included 140 teachers based on sample calculations. The age of participants ranged between 24 and 60 years. A questionnaire was used to collect demographic data about the lifestyle, past medical, and family histories. Serum lipid profile, and fasting blood glucose levels for each participant were measured. Lipoprotein levels were categorized based on the adult treatment panel III criteria. Results The overall prevalence of dyslipidemia among Palestinian men was 66.4%. The most prevalent type of dyslipidemia was hypo HDL (X < 40 mg/dl, 59.3%), followed by hypertriglyceridemia (X ≥ 200 mg/dl, 20%). The prevalence of hyper LDL (X ≥ 160 mg/dl), hypercholesterolemia (X ≥ 240 mg/dl) was 8.5%, and 3.6%, respectively. About 15% of participants had glucose intolerance, and 4.3% had hyperglycemia (undiagnosed). Those with glucose intolerance, 13 (9.2%) have hypo HDL, while 9 (6.42%) have hypertriglyceridemia. On the other hand, out of hyperglycemic patients: 5 (3.5%) had hypo HDL, and 1 (0.7%) had hypertriglyceridemia. Conclusion Around two-thirds of undiagnosed participants had at least one lipid abnormality. None of them were aware of having dyslipidemia. The prevalence of undiagnosed dyslipidemia was higher than the prevalence of undiagnosed glucose intolerance, and diabetes. This suggests that dyslipidemia plays a major role in developing diabetes. Hence, profound efforts should be done to manage and treat those with dyslipidemia, in order to prevent progression to type II diabetes mellitus.
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来源期刊
Journal of Lipids
Journal of Lipids BIOCHEMISTRY & MOLECULAR BIOLOGY-
自引率
0.00%
发文量
7
审稿时长
12 weeks
期刊介绍: Journal of Lipids is a peer-reviewed, Open Access journal that publishes original research articles and review articles related to all aspects of lipids, including their biochemistry, synthesis, function in health and disease, and nutrition. As an interdisciplinary journal, Journal of Lipids aims to provide a forum for scientists, physicians, nutritionists, and other relevant health professionals.
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