富血小板纤维蛋白(PRF)在下颌第三磨牙拔牙后的有效性:一项系统综述

A. Rahman, Tamiral Jannat
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引用次数: 0

摘要

(1)目的:富血小板纤维蛋白(PRF)在拔牙槽内的应用已被证明有助于组织愈合。它还能最大限度地减少有害后果。本系统综述的基本原理是观察PRF的使用与下颌第三磨牙手术后的术后后果之间可能的关联。(2)材料和方法:电子检索以下数据库(截至2021年2月28日):PubMed、Cochrane图书馆、Embase、国际临床试验注册平台(ICTRP)和ClinicalTrials.gov。手工探索完成了各种期刊关于口腔颌面外科的主题。在线搜索应用了关键词“富血小板纤维蛋白或PRF”和“下颌第三磨牙”。为了回顾PRF的有效性,我们收集了术后伴随的后果:疼痛、肿胀、牙关、切间距离、镇痛消耗、软组织愈合、骨愈合、窝窝并发症和牙周参数。(3)结果:26篇全文研究中仅有9篇纳入综述进行定性分析。所有研究均为随机临床试验(rct),其中8项裂口设计和1项平行设计研究。通常在疼痛、术后肿胀、开口、牙周袋深度、软组织愈合、牙槽骨炎或干槽发生率等方面观察到显著的结果,但并不总是如此。定性审查表明,PRF在骨愈合方面没有显著的效果。(4)结论:局部应用PRF是缓解下颌第三磨牙拔牙后疼痛、牙关、水肿和促进软组织愈合的一种实用方法。PRF在拔牙后的骨愈合中往往没有作用。需要更多的对照临床试验和随机对照试验来探索下颌第三磨牙拔除后PRF的最终结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effectiveness of Platelet-Rich Fibrin (PRF) Following Mandibular Third Molar Extraction: A Systematic Review
(1) Purpose: The employment of platelet-rich fibrin (PRF) in the extracted teeth socket has been shown to aid tissue healing. It also minimizes detrimental consequences. The rationale of this systematic review is to observe the possible association between PRF employment and postoperative consequences following mandibular third molar surgery. (2) Materials and Methods: The following databases were explored electronically (till 28 February 2021): PubMed, Cochrane library, Embase, International Clinical Trials Registry Platform (ICTRP), and ClinicalTrials.gov. A manual explore was accomplished on various journals regarding the subject of oral and maxillofacial surgery. The online explore applied the keywords “platelet-rich fibrin or PRF,” and “mandibular third molar.” To review the efficiency of PRF, the accompanying post-operative consequences were collected: pain, swelling, trismus, inter-incisal distance, analgesic consumption, soft tissue healing, bone healing, socket complications, and periodontal parameters. (3) Results: Just 9 full-text studies out of 26 were comprised of review for qualitative analysis. All of the studies were randomized clinical trials (RCTs), with eight split-mouth designs and one parallel design study. Significant outcomes were usually observed for pain, postoperative swelling, mouth opening, periodontal pocket depth, soft tissue healing, and the incidence of alveolar osteitis or dry sockets, but not constantly. The qualitative scrutiny disclosed that the PRF had no considerable outcome in bone healing. (4) Conclusions: Local administration of PRF is a practical way of alleviating pain, trismus, oedema, and enhancing soft tissue healing following mandibular third molar extraction. PRF tends to have no function in bone healing following extraction. More controlled clinical trials and RCTs are necessitating exploring the end results of PRF following mandibular third molar extraction.
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