儿童耳膜外转移:临床病例

Л. В. Ольхова, О. Г. Желудкова, В. Е. Попов, Алексей Николаевич Кисляков, Т. В. Басалай, С. В. Горбатых, Д. А. Скобеев, Н. И. Зелинская
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引用次数: 0

摘要

背景。室管膜瘤是一组神经胶质肿瘤,通常发生于颅后窝,较少发生于侧脑室和脊髓。大多数情况下,室管膜瘤复发发生在原发部位或中枢神经系统(CNS)。室管膜瘤转移到颅脊髓系统以外的情况很少发生。临床病例描述。本文报告一例10岁幕上间变性室管膜瘤患者经综合治疗后发生神经外转移至骨及骨髓的临床病例。对已发表的儿童神经外室管膜瘤转移的病例进行了综述。人们试图考虑影响其发展的可能风险因素。结论。室管膜肿瘤能够神经外转移到骨和造血系统。持续的生长和转移导致该疾病的预后极为不利。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Экстраневральное метастазирование эпендимомы у детей: клинический случай
Background . Ependymomas are a group of glial tumours, usually occurring in the posterior cranial fossa, less often — in the lateral ventricles and spinal cord. Most often, the recurrence of ependymomas occurs in primary sites, or in the central nervous system (CNS). Ependymoma metastasis beyond the craniospinal system occurs rarely if ever. Description of a Clinical Case . A clinical example of extraneural metastasis to the bones and bone marrow in a 10-year-old patient with supratentorial anaplastic ependymoma after complex therapy has been presented. A review of published cases of the development of extraneural ependymoma metastasis in children has been presented. An attempt was made to consider possible risk factors for their development.  Conclusion . Ependymal tumours are capable of extraneural metastasis to the bone and hematopoietic systems. Continued growth and metastasis lead to extremely unfavourable prognosis for the disease.
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