二甲双胍在DM2中的分子机制——一个新的假说

International Journal of Biochemistry Research and Review Pub Date : 2018-02-06 DOI:10.9734/IJBCRR/2017/39028

A. Prasad

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摘要

二甲双胍，一种抗高血糖药物，虽然从1957年起就开始使用，但至今仍不清楚其作用机制。即使是在amp刺激的蛋白激酶(AMPK)刺激和电子传递链(ETC)复合体1的抑制机制中，也有一些事实，但不是全部事实，因为有反对意见，尚未解决。随后的创新机制，如

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Molecular Mechanism of Metformin in DM2- A New Hypothesis

Metformin, the antihyperglycaemic drug, though in use since 1957 eluded as to its mechanism of action till date. There is some truth but not the whole truth, in even the much-favoured mechanisms of AMP-stimulated protein kinase (AMPK) stimulation and inhibition of complex 1 of Electron Transport Chain (ETC), as there are objections, unresolved, as yet. Subsequent innovative mechanisms, like

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International Journal of Biochemistry Research and Review

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