Acute hepatic failure with hemolytic anemia due to Hepatitis A infection with coexistent glucose-6-phosphate dehydrogenase deficiency

Though only 0.1% of acute viral Hepatitis A complicated as acute hepatic failure, Hepatitis A has been detected as the most common aetiology of acute hepatic failure in India. Any co-existence morbidity like G6PD deficiency certainly makes it more complicated. Here we present a case where a 10 year old boy admitted with Acute Hepatic Failure with grade 3 encephalopathy with severe hyperbilirubinemia and haemolytic anemia with features of acute tubular necrosis and later on found to be G6PD deficient.