J. Lee, Tahmarah Otoo, Marisol Brito, Amanda Jaimes, Arlene Martínez, J. Trevitt
{"title":"高糖高饱和脂肪饮食对老年Sprague-Dawley大鼠学习能力的影响","authors":"J. Lee, Tahmarah Otoo, Marisol Brito, Amanda Jaimes, Arlene Martínez, J. Trevitt","doi":"10.32398/cjhp.v19i1.2653","DOIUrl":null,"url":null,"abstract":"With an increase in longevity, many studies have explored the influences of different lifestyle factors on successful aging. This study hypothesizes that older rats fed with a nutritionally balanced standard diet would perform better on learning tasks than rats fed with either a high-sucrose or a high-saturated fat. It also hypothesizes that older rats fed with a high-sucrose diet would perform better than those fed with a high-saturated fat. The learning abilities of the 15-month-old rats (N = 36) were assessed by conducting forward and reverse learning tasks using a T-maze apparatus. The results showed that rats on a nutritionally balanced diet performed significantly better on both learning tasks than those on either the high-sucrose or the high-saturated fat (p’s < .05). This may be due to the fact that the high-sucrose and high-saturated fat diets exacerbated a cognitive decline in geriatric rats. There was no significant difference between the learning abilities of the rats on a high-sucrose or high-saturated fat diet (p’s > .05). This finding suggests that, at an older age, both high-sucrose and high-saturated fat diets have a similarly detrimental influence on cognitive health.","PeriodicalId":87431,"journal":{"name":"Californian journal of health promotion","volume":"79 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Effects of High-Sucrose and High-Saturated Fat Diets on Learning Abilities in Old Sprague-Dawley Rats\",\"authors\":\"J. Lee, Tahmarah Otoo, Marisol Brito, Amanda Jaimes, Arlene Martínez, J. Trevitt\",\"doi\":\"10.32398/cjhp.v19i1.2653\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"With an increase in longevity, many studies have explored the influences of different lifestyle factors on successful aging. This study hypothesizes that older rats fed with a nutritionally balanced standard diet would perform better on learning tasks than rats fed with either a high-sucrose or a high-saturated fat. It also hypothesizes that older rats fed with a high-sucrose diet would perform better than those fed with a high-saturated fat. The learning abilities of the 15-month-old rats (N = 36) were assessed by conducting forward and reverse learning tasks using a T-maze apparatus. The results showed that rats on a nutritionally balanced diet performed significantly better on both learning tasks than those on either the high-sucrose or the high-saturated fat (p’s < .05). This may be due to the fact that the high-sucrose and high-saturated fat diets exacerbated a cognitive decline in geriatric rats. There was no significant difference between the learning abilities of the rats on a high-sucrose or high-saturated fat diet (p’s > .05). This finding suggests that, at an older age, both high-sucrose and high-saturated fat diets have a similarly detrimental influence on cognitive health.\",\"PeriodicalId\":87431,\"journal\":{\"name\":\"Californian journal of health promotion\",\"volume\":\"79 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Californian journal of health promotion\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32398/cjhp.v19i1.2653\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Californian journal of health promotion","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32398/cjhp.v19i1.2653","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of High-Sucrose and High-Saturated Fat Diets on Learning Abilities in Old Sprague-Dawley Rats
With an increase in longevity, many studies have explored the influences of different lifestyle factors on successful aging. This study hypothesizes that older rats fed with a nutritionally balanced standard diet would perform better on learning tasks than rats fed with either a high-sucrose or a high-saturated fat. It also hypothesizes that older rats fed with a high-sucrose diet would perform better than those fed with a high-saturated fat. The learning abilities of the 15-month-old rats (N = 36) were assessed by conducting forward and reverse learning tasks using a T-maze apparatus. The results showed that rats on a nutritionally balanced diet performed significantly better on both learning tasks than those on either the high-sucrose or the high-saturated fat (p’s < .05). This may be due to the fact that the high-sucrose and high-saturated fat diets exacerbated a cognitive decline in geriatric rats. There was no significant difference between the learning abilities of the rats on a high-sucrose or high-saturated fat diet (p’s > .05). This finding suggests that, at an older age, both high-sucrose and high-saturated fat diets have a similarly detrimental influence on cognitive health.