基于图像相关法的微循环血流测量系统

Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Pub Date : 1996-12-01 DOI:10.1109/IEMBS.1996.651927

K. Tsukada, H. Minamitani, E. Sekizuka, C. Oshio

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引用次数: 1

摘要

微循环系统是组织和器官中物质运输的重要组成部分，为了阐明微循环系统的功能，了解微血管中的血流速度及其分布是非常重要的。建立了一种测量微循环中红细胞速度的图像相关方法。使用高速视频系统在显微镜下原位获得血流的动态图像，并使用PC系统处理以测量红细胞速度。结果表明，该系统能够以高时间分辨率分析红细胞速度。该系统适用于肝、肾及肠系膜红细胞流速的测量。给自发性高血压大鼠(SHR)服用抗高血压药，观察血流变化。作者能够证明该系统是有效的药理学评价。

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Blood flow measurement system for microcirculation by image correlation method

In order to elucidate the function of microcirculation system, which is essential for material transport in tissues and organs, it is very important to know blood flow velocity and its distribution in the microvessels. An image correlation method has been developed for the measurement of red blood cell (RBC) velocity in the microcirculation. Dynamic images of the blood flow are obtained in situ under microscopic observation using a high-speed video system and are processed to measure RBC velocity with a PC system. The results indicate that this system enable to analyze RBC velocity with a high-temporal resolution. This system is applied to RBC velocity measurements in liver and kidney as well as in mesentery. An anti-hypertensive agent is administered to spontaneously hypertensive rats (SHR), and blood flow change is observed. The authors are able to show that this system is effective for pharmacological evaluation.

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Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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