经颅直接刺激控制帕金森病主要症状的神经调节:一个案例研究

L. Dall’Agnol, Alice Medeiros de Souza, Lilian Campos Amadeu, Eleni Vosniadou, F. I. Corrêa
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引用次数: 0

摘要

帕金森病(PD)是一种中枢神经系统神经退行性疾病,主要影响运动系统,降低运动协调、平衡和产生震颤,并逐渐丧失日常活动能力,包括行走。本研究旨在验证经颅直流电刺激(tDCS)对帕金森病患者平衡、运动控制和生活质量的影响。患者接受了三次治疗,包括10次,每次20分钟,治疗间隔一周。在初级运动皮层(M1)、背外侧前额叶皮层(DLPFC)和背外侧前额叶皮层(D Sham-tDCS)上施加主动刺激。通过不同的量表和问卷评估,DLPFC刺激在运动控制、平衡、步态和整体PD症状方面产生了最好的改善。因此,主动刺激DLPFC产生了更好的结果,并可能有助于治疗帕金森病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TRANSCRANIAL DIRECT STIMULATION IN THE NEUROMODULATION OF CONTROLLING MAIN SYMPTOMS OF PARKINSON’S DISEASE: A CASE STUDY
Parkinson’s disease (PD) is a central nervous system neurodegenerative disorder that primarily affects the motor system, decreasing motor coordination, balance and generating tremors, and a progressive loss of everyday mobility, including walking. This study was conducted to verify the effects of Transcranial Direct Current Stimulation (tDCS) on balance, motor control, and the quality of life in Parkinson’s disease patients. The patient received three treatments consisting of 10 sessions of 20 minutes each and a one-week interval between treatments. Active stimulation was applied on the primary motor cortex (M1), the dorsolateral prefrontal cortex (DLPFC), and the dorsolateral prefrontal cortex (D Sham-tDCS. DLPFC stimulation produced the best improvements in terms of motor control, balance, gait, and overall PD symptoms, as evaluated by different scales and questionnaires. As a result, active stimulation of the DLPFC produced superior outcomes and may contribute to treating Parkinson’s disease.
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