单光子发射计算机断层心肌成像精确定量的优化

K. Alzimami, N. Abuhadi, A. Alanazi, O. Kadri, A. Alfuraih, Z. Podolyák, D. Bradley, M. Mahmoud, S. Sassi
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引用次数: 0

摘要

目的:心肌单光子发射计算机断层扫描(SPECT)的广泛可用性和准确性声誉使其成为核心脏病学程序的全球首选。本研究的目的是确定3D迭代重建算法的有效性和可测量的准确性,与心脏SPECT图像的滤波后投影技术相比。有效性取决于各种技术产生准确的心脏SPECT图像的能力。材料和方法:使用西门子Symbia T16 SPECT/CT扫描仪获取SPECT/CT图像和蒙特卡罗模拟,同时使用GATE包实现Infinia™(GE)双头SPECT伽马相机模拟数据。从点源和线源获得记录,并创建心脏插入物,同时模拟计算机化的幻影XCAT。结果:本研究的结果证明了图像质量的改善,使用Flash 3D算法相对于FBP技术提高了其准确性。本文提供的数据进一步表明,心肌图像的图像质量和定量精度,特别是使用Flash 3D算法重建的高分辨率研究,会受到呼吸引起的运动的极大影响。结论:采用呼吸门控技术,利用带衰减和散射校正的有序子集最大化(OSEM)算法可以更好地提高图像质量和定量精度。模拟呼吸引起的运动导致重建SPECT记录,Flash 3D的量化图像分辨率降低73%,FBP的量化图像分辨率降低43%。它还导致使用FBP和Flash 3D对左心室体积的低估分别为18%和41%。总之,我们的物理幻影研究和蒙特卡罗模拟研究与我们研究的主要假设一致。与FBP技术相比,使用Flash 3D算法可以提高图像质量和精度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimization of Accurate Quantification in Single-Photon Emission Computed Tomography Myocardial Imaging
Purpose: The wide availability and reputation for accuracy of the single-photon emission computed tomography (SPECT) of the myocardium has made it a top global choice for nuclear cardiology procedures. The goal of this research is to determine the effectiveness and measurable accuracy of 3D iterative reconstruction algorithms compared to filtered back projection techniques for cardiac SPECT images. Effectiveness is determined by the ability of the various techniques to produce accurate cardiac SPECT images. Materials and Methods: A Siemens Symbia T16 SPECT/CT scanner was used to acquire SPECT/CT images and the Monte Carlo simulations whilst a GATE package was used with the implementation of Infinia™ (GE) dual head SPECT gamma camera–simulated data. The recordings were acquired from point and linear sources and a cardiac insert was created along with a simulation of a computerized phantom XCAT. Result: The results of this study demonstrated an improvement in image quality and the use of a Flash 3D algorithm relative to FBP technique enhances its accuracy. The data presented in this article further show that the image quality of myocardium images and quantification accuracy, particularly for high-resolution studies reconstructed using the Flash 3D algorithm, can be greatly affected by a respiratory-induced motion. Conclusion: Image quality and quantification accuracy can be better improved with respiratory-gating techniques, utilization of ordered-subsets maximization (OSEM) algorithms with attenuation and scatter correction. A simulation of respiratory-induced motion resulted in a reconstructed SPECT recording of 73% reduction in the quantified image resolution for Flash 3D and 43% for FBP. It also caused the underestimation for the left ventricle volume by 18% using FBP and 41% for the Flash 3D. In conclusion, our physical phantom studies and Monte Carlo simulation studies agree with the main hypothesis of our investigation. They showed improvement in image quality with increased accuracy when using the Flash 3D algorithm relative to the FBP technique.
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来源期刊
Journal of Medical Imaging and Health Informatics
Journal of Medical Imaging and Health Informatics MATHEMATICAL & COMPUTATIONAL BIOLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Journal of Medical Imaging and Health Informatics (JMIHI) is a medium to disseminate novel experimental and theoretical research results in the field of biomedicine, biology, clinical, rehabilitation engineering, medical image processing, bio-computing, D2H2, and other health related areas. As an example, the Distributed Diagnosis and Home Healthcare (D2H2) aims to improve the quality of patient care and patient wellness by transforming the delivery of healthcare from a central, hospital-based system to one that is more distributed and home-based. Different medical imaging modalities used for extraction of information from MRI, CT, ultrasound, X-ray, thermal, molecular and fusion of its techniques is the focus of this journal.
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