对默克尔细胞癌的认识:考虑一下

B. Pina
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引用次数: 0

摘要

我们提出的情况下,一个71岁的白人男性抱怨左外侧下眼睑肿胀后,昆虫叮咬的感觉。体格检查示椭圆形病变(直径半厘米),可移动,边缘清晰,软稠度,有红斑。触诊无痛,未累及淋巴结。患者有转移性前列腺癌病史。一周后,病变快速生长(直径2厘米)并伴有中枢性溃疡。行切口活检。免疫组化结果提示原发性神经内分泌癌:默克尔细胞癌。患者接受了广泛的局部切除、局部淋巴结切除和眼睑重建手术。对这类肿瘤的认识至关重要。诊断延误严重影响疾病的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
AWARENESS FOR MERKEL CELL CARCINOMA: CONSIDER IT
We present a case of a 71-year-old Caucasian male complaining of left lateral lower eyelid swelling after an insect sting sensation. Physical examination showed an oval shaped lesion (diameter of half a centimetre), mobile, with well-defined edges, soft consistency and erythema. Palpation was painless and without node involvement. The patient had history of metastatic prostate adenocarcinoma. One week later, the lesion showed rapid growth (diameter of two centimetres) with central ulceration. Incisional biopsy was made. Immunohistochemistry findings were suggestive of a primary neuroendocrine carcinoma: Merkel Cell Carcinoma. The patient underwent surgery with wide local excision, regional lymphadenectomy and eyelid reconstruction. Awareness to this type of tumour is crucial. A delay in diagnosis affects significantly the prognosis of the disease.
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