同一群囊胚玻璃化前后双滋养外胚层活检成功着床及活产首例

Q4 Medicine
Harsha Bhadarka, NayanaH Patel, Yuvraj D Jadeja, K. Patel, Niket Patel, M. Patel, K. Rao
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引用次数: 0

摘要

简介:报道我们所知的首例在玻璃化前后对同一群囊胚进行双滋养外胚层活检后活产的病例。设计:病例报告。患者:36岁女性,已婚13年,治疗不孕症。主要观察指标:双滋养外胚层活检后活产。结果:玻璃化前后双活检及阳性结果。结论:胚胎着床前遗传学筛查和诊断(PGS/PGD)虽然是一种对胚胎的侵入性手术,但如果做得很仔细,不会影响胚胎的着床潜力,对于PGS/PGD报告不确定或疑似假阳性的胚胎,第二次活检可能是一种可行的选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
First Case of Successful Implantation and Live Birth after Double Trophectoderm Biopsy before and after Vitrification on the Same Cohort of Blastocyst
Introduction: To report the first case of live birth after double trophectoderm biopsy before and after vitrification on the same cohort of blastocyst in our knowledge. Design: Case report. Patient: A 36-year-old female with a history of 13 years of active married life for treatment of infertility. Main outcome measure: Live birth after double trophectoderm biopsy. Results: Double biopsy preand postvitrification and its positive outcome. Conclusion: Preimplantation genetic screening and diagnosis (PGS/PGD), though an invasive procedure on the embryos, when done meticulously would not dampen the implantation potential of the embryo and second biopsy could be a feasible option to salvage embryos with inconclusive or suspected falsepositive PGS/PGD reports.
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