牙科医师治疗癌症病人的策略:叙述性文献回顾

H. Antunes, L. D. B. Alves, Ana C S Menezes, A. Costa, F. Heimlich, D. Goldemberg
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摘要

目的:介绍预防、诊断和治疗与癌症治疗相关的口腔毒性所必需的牙科程序。材料和方法:对感兴趣的主题进行了叙述文献综述。对葡萄牙语和英语的文章进行了调查,没有出版年份的限制,全文可以在Pubmed、Scielo、Cochrane和Google Scholar数据库中找到。结果:本次检索共纳入100篇文章,包括9篇系统综述、3篇系统综述结合meta分析、48篇文献综述、3篇随机临床试验、4篇前瞻性队列、12篇回顾性队列、5篇横断面研究、2篇病例对照研究、5篇病例报告、7篇专家共识小组、1篇致编辑信和1篇定性研究,均发表于1976年至2020年之间。根据治疗方式(头颈癌的手术和放疗、化疗、造血干细胞移植和抗吸收药物的使用)和治疗时间(每次治疗前、期间或之后)对牙科手术进行分类。结论:咨询的文章一致认为癌症患者在治疗前、治疗中和治疗后需要牙科护理,强调了在肿瘤患者护理团队中加入专业牙科医生的重要性;因此,该专业人员应采取预防、早期诊断和治疗口服毒性的行动,以尽量减少其后果并改善患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Strategies for the dentist management of cancer patients: narrative literature review 
Aim: To present the dental procedures necessary for the prevention, diagnosis, and treatment of oral toxicities related to cancer treatment. Material and methods: A narrative literature review was carried out regarding the topics of interest. Articles in Portuguese and English, without the restriction of the year of publication and full text available in the databases Pubmed, Scielo, Cochrane, and Google Scholar were investigated. Results: Through this search, 100 articles were selected, consisting of 9 systematic reviews, 3 systematic reviews with meta-analysis, 48 literature reviews, 3 randomized clinical trials, 4 prospective cohorts, 12 retrospective cohorts, 5 cross-sectional studies, 2 case-control studies, 5 case reports, 7 expert consensus panels, 1 letter to the editor and 1 qualitative study, published between 1976 and 2020. Dental procedures were classified according to the therapeutic modality (surgery and radiotherapy for head and neck cancer, chemotherapy, hematopoietic stem cell transplantation, and use of antiresorptive medications) and the time of treatment (prior, during, or after each one). Conclusions: The consulted articles were unanimous regarding the need for dental care for cancer patients in the pre, trans, and post-treatment, highlighting the importance of inserting specialized dental surgeons in the oncology patient care team; thus, this professional should act in the prevention, early diagnosis, and treatment of oral toxicities, to minimize their consequences and improve patients’ quality of life.
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