莫沙必利:一种促动力学药物

C. Bhan, R. Saraswat
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引用次数: 2

摘要

胃促动力剂是一种通过刺激小肠蠕动或收缩的频率来增强胃肠运动的药物。应该注意的是,它们的节奏完全没有受到干扰。腹部不适、便秘、烧心、恶心、呕吐、划船等胃肠道症状均可通过这些药物得到缓解。促动力剂也有助于缓解上述运动障碍。莫沙必利是一种选择性5-HT4受体拮抗剂,对5-HT1、5- ht2及其他受体如多巴胺d2受体、肾上腺素el1和肾上腺素el2受体无亲和力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SHORT REVIEW ON MOSAPRIDE: A PROKINETIC AGENT
A gastroprokinetic or gastrokinetic or prokinetic agent is a drug which enhances gastrointestinal motility by stimulating the frequency of peristalsis or contractions in the small intestine. It should be noted that their rhythm is not disturbed at all.Abdominal discomfort, constipation, heart burn,nausea, vomiting, boating and other gastrointestinal symptoms are relieved by these agents.Prokinetic agents also help in relieving above mentioned motility disorders. Mosapride is a selective 5-HT4 receptor antagonist with no affinity for 5-HT1,5-HT2and other receptors such as dopamine D2-Receptors,adrenalineL1and adrenalineL2 receptors.
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