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引用次数: 0
摘要
在现代风湿病学中,合并症感染对发病率和死亡率有重要影响,特别是在免疫炎症性风湿病(IIRD)中。解决这一问题的方法之一是研究和积极使用各种疫苗。本文分析了2022年美国风湿病学会(American College of Rheumatology, ACR)专家提出的急性呼吸道感染患者疫苗接种建议。疫苗接种的安全性和免疫原性与预防各种感染的IVR患者进行了讨论。需要强调的是,在疫苗接种之前或之后暂停服用该药的决定应考虑到现有的IIRD、其活性和疫苗控制感染的风险。任何疫苗接种策略(特别是有条件的建议)的一个关键组成部分是与患者共同决策。展望了今后研究的主要方向。
Vaccination for rheumatic diseases: Current issues (based on ACR guidelines)
In modern rheumatology, comorbid infections have a significant impact on morbidity and mortality, especially in immuno-inflammatory rheumatic diseases (IIRD). One of the ways to solve this problem is the study and active use of various vaccines. This article analyzes the recommendations for vaccination of patients with acute respiratory infections, proposed in 2022 by experts of the American College of Rheumatology (ACR). The safety and immunogenicity of vaccination associated with the prevention of various infections in patients with IVR are discussed. It is emphasized that the decision to suspend taking the drug before or after vaccination should be made taking into account the existing IIRD, its activity and the risk of vaccine-controlled infection. A key component of any vaccination strategy (especially for conditional recommendations) is decision-making together with the patient. The main directions of future research on the problem under consideration are outlined.