鼻支气管变态反应患者皮肤点刺试验对常见变态反应原敏感性的研究

S. Karmakar, K. Raza, R. Prasad
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引用次数: 5

摘要

背景:鼻支气管过敏是世界范围内重要的过敏负担。鼻支气管变态反应的发生率越来越高,因此我们对这组患者采用皮肤点刺试验(SPT)法对常见变态反应原进行观察研究。目的:采用SPT法研究鼻支气管变态反应患者皮肤对各种过敏原的敏感性。材料与方法:使用60种过敏原对100例鼻支气管过敏患者进行6000次SPTs。结果:本组患者以男性为主,以21 ~ 30岁年龄组鼻支气管过敏最为常见。在所研究的各种过敏原中,昆虫(24%)是最常见的过敏原,其次是尘螨(20%)、空气粉尘(11.3%)、花粉(7.75%)、真菌(6%)、皮屑(6%)、蚕丝(4%)、多汁食物(2.4%)和非多汁食物(2.25%)。昆虫中,常见的过敏原为飞蛾(30)。粉尘中,谷物粉尘(30)是常见的过敏原。花粉中以决明子(Cassia siamea, 20)最为常见。烟曲霉(Aspergillus fumigatus, 16)是最常见的引起敏感性的真菌。在各种各样的食物(多汁的和不多汁的)中,牛奶、杏仁和腰果(每种4个)是常见的过敏原。结论:皮肤点刺试验是过敏综合治疗的重要组成部分。我们的研究确定皮肤对各种过敏原的敏感性,以避免治疗和免疫治疗受影响的患者。在我们的研究中发现,对昆虫过敏是最常见的,可能是因为印度环境中普遍存在的卫生条件差和过度拥挤的住房。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A study of skin prick test sensitivity to common allergens in patients of nasobronchial allergy
BACKGROUND: Nasobronchial allergy accounts for a significant burden of allergy all over the world. The prevalence of nasobronchial allergy is increasing, so we conducted an observational study of common allergens by skin prick test (SPT) method in this group of patients. OBJECTIVE: The objective is to study skin sensitivity to various allergens in patients of nasobronchial allergy, using SPT method. MATERIALS AND METHODS: A total of 6000 SPTs were done using 60 allergens on 100 patients of nasobronchial allergy. RESULTS: Males were the predominant group of patients, and nasobronchial allergy was most common in 21–30 years' age group in our study. Among various groups of allergens studied, insects (24%) were the most common offending allergens, followed by dust mite (20%), airborne dust (11.3%), pollens (7.75%), fungi (6%), dander (6%), silk (4%), juicy foods (2.4%), and nonjuicy foods (2.25%). Among insects, moth (30) was the common allergen. Among dust, grain dust (30) was the common allergen. Among pollens, Cassia siamea (20) was most common. Aspergillus fumigatus (16) was the most common fungus to which sensitivity was elicited. Among miscellaneous foods (juicy and nonjuicy), milk, almonds, and cashew nut (4 each) were the common allergens. CONCLUSION: Skin prick testing forms an essential part of a comprehensive approach for allergy remediation. Our study determined skin sensitivity to various allergens for avoidance therapy and immunotherapy in affected patients. Allergy to insects as found in our study to be most common is likely because of prevailing poor sanitation and overcrowded dwellings in the Indian milieu.
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