牙周病是Covid-19严重疾病的危险因素

D. Kim
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摘要

牙周病(PD)包括一组涉及宿主炎症方面和影响牙周组织并可能具有全身性影响的益生菌不良事件的疾病。多种因素和合并症与PD密切相关,如糖尿病、肥胖、衰老、高血压等;虽然,潜在的机制或因果关系尚未完全确定。有趣的是,这些相同的因素与由冠状病毒SARS-CoV-2引起的疾病2019年严重冠状病毒病(COVID-19)的进展广泛相关。由于炎症和益生不良因素以及合共病会影响全身健康,因此牙周状况可能表明COVID-19并发症的风险。然而,尚未报道对COVID-19患者的口腔健康史(包括牙周状况)进行评估。牙周病是一组慢性炎症性疾病,包括牙龈炎和牙周炎。这些疾病是由几种引起炎症和破坏牙齿支持组织的微生物引起的。根据世界卫生组织(WHO)的数据,PD影响着全球10%的人口。口腔卫生不良、吸烟、糖尿病、药物、年龄、遗传和肥胖与帕金森病的风险增加有关。同样,其他研究表明PD与其他疾病如糖尿病、高血压、哮喘、肝病等之间存在关联。COVID-19是一种由新型冠状病毒SARSCoV-2引起的疾病,会引发肺部和其他器官的损伤。大多数COVID-19患者症状轻微;然而,少数人可能会发展成严重的疾病,如肺炎、肺水肿、急性呼吸窘迫综合征(ARDS)、多器官功能障碍综合征,甚至死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Periodontal Sickness a Danger Factor For Serious Covid-19 Ailment
Periodontal Disease (PD) comprises a group of diseases involving inflammatory aspects of the host and dysbiotic events that affect periodontal tissues and could have systemic implications. Diverse factors and comorbidities have been closely associated with PD such as diabetes, obesity, aging, hypertension, and so on; although, underlying mechanisms or causal associations have not been established completely. Interestingly, these same factors have been widely associated with progression or severe coronavirus disease 2019 (COVID-19), an illness caused by coronavirus SARS-CoV-2. Since inflammatory and dysbiotic factors as well as comorbidities affect systemic health, it is possible that periodontal status indicates the risk of complication of COVID-19. However, assessment of oral health history including periodontal status in COVID-19 patients has not been reported. Periodontal diseases are a group of chronic inflammatory diseases, including gingivitis and periodontitis. These diseases are driven by several microbial agents that cause inflammation and destruction of tooth-supporting tissues. According to the World Health Organization (WHO), PD affects 10% of the global population. Poor oral hygiene, tobacco smoking, diabetes, medication, age, hereditary, and obesity have been related to increasing the risk of PD. Similarly, other studies suggest the association between PD and other diseases such as diabetes, hypertension, asthma, liver diseases, among others. COVID-19 is a disease caused by novel coronavirus named SARSCoV-2 that triggers damage to the lungs and other organs. Most COVID-19 patients present mild symptoms; however, a few could develop severe illness having pneumonia, pulmonary edema, Acute Respiratory Distress Syndrome (ARDS), multiple organ dysfunction syndromes, or even die.
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