青少年男性复发性丘疹性坏死结核:诊断困境

Arundhathi Shankaralingappa, M. Anthony, T. Santosh, K. Josephain, Prabhakaran Nagendran, Hima Gopinath
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引用次数: 0

摘要

结核被认为是对内源性结核(TB)的超敏反应。丘疹坏死结核(PNT)是一种罕见的结核,发生率<5%的活动性结核。一位18岁的男性,在四肢、躯干和颈部复发性坏死性丘疹6年,愈合后伴有疤痕。病变活检显示干酪样肉芽肿伴淋巴组织细胞性血管炎。Ziehl-Neelsen染色抗酸杆菌阴性,Mantoux染色强阳性。由于资金限制,聚合酶链反应没有进行。最终确诊为PNT,患者开始接受抗结核治疗(ATT),治疗有效果。PNT应作为前哨病变来治疗,并应仔细检查是否累及全身结核。对PNT的认识对其诊断和在适当的时候建立ATT至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recurrent papulonecrotic tuberculid in an adolescent male: A diagnostic dilemma
Tuberculids are considered to be a hypersensitivity reaction to endogenous tuberculosis (TB). Papulonecrotic tuberculid (PNT) is a rare tuberculid occurring in <5% of active TB. An 18-year-old male presented with recurrent necrotic papules for 6 years on limbs, trunk, and neck which healed with scars. Biopsy from lesion revealed caseating granulomas with lymphohistiocytic vasculitis. Ziehl–Neelsen stain was negative for acid-fast bacilli, but Mantoux was strongly positive. The polymerase chain reaction was not done due to monetary constraints. The final diagnosis of PNT was confirmed and he was started on anti-tubercular treatment (ATT) for which he responded. PNT should be treated as a sentinel lesion and a meticulous search for systemic involvement of TB should be carried out. Awareness about PNT is essential for its diagnosis and to institute ATT at appropriate time.
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