血液透析41年后的活体肾移植

Q4 Medicine
Kosuke Tanaka, Y. Hidaka, Shigeyoshi Yamanaga, Kohei Kinoshita, Akari Kaba, M. Toyoda, H. Yokomizo
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引用次数: 1

摘要

由于膀胱萎缩,长期透析患者在肾移植后出现膀胱输尿管反流和并发尿路感染。一位58岁的女性在透析41年后接受了活体肾移植。患者无禁忌症,尽管有长期血液透析史,但心功能良好,动脉钙化极少。免疫抑制开始使用他克莫司、霉酚酸酯、强的松龙和basiliximab。由于患者膀胱容量为15ml,我们采用抗反流技术进行输尿管膀胱造口术。术后临床过程顺利,移植物立即恢复功能。术后3周膀胱体积逐渐增大至81 mL。患者移植后早期因尿频而出现抑郁,但膀胱容量逐渐增大至400ml后很快恢复。患者尚未报告发生尿路感染。本病例强调了活体肾移植诱导膀胱功能的恢复,尽管有长期的透析史,但需要谨慎的输尿管膀胱造瘘术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Living Donor Kidney Transplantation for a Recipient after 41 Years of Hemodialysis
Due to atrophic bladder, patients undergoing long-term dialysis experience vesicoureteral reflux and complicated urinary tract infections after kidney transplantation. A 58-year-old woman underwent living donor kidney transplantation after 41 years of dialysis. She had no contraindications, with good cardiac function and minimal artery calcification despite the long history of hemodialysis. Immunosuppression was initiated with tacrolimus, mycophenolate mofetil, prednisolone, and basiliximab. Ureteroneocystostomy with an antireflux technique was carefully conducted as her bladder volume was 15 mL. The postoperative clinical course was uneventful with immediate graft function. The bladder volume gradually increased to 81 mL at discharge, 3 weeks postoperatively. The patient was initially depressed due to frequent urination early post-transplant but recovered soon after as the bladder volume gradually increased to 400 mL. The patient has not yet reported a urinary tract infection episode. This case highlights living donor kidney transplantation-induced recovery of bladder function with careful ureteroneocystostomy, despite the long dialysis history.
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来源期刊
Cell and Organ Transplantology
Cell and Organ Transplantology Medicine-Transplantation
CiteScore
0.40
自引率
0.00%
发文量
8
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