动脉粥样硬化的分子影像学

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL

University of Toronto Medical Journal Pub Date : 2010-02-14 DOI:10.5015/UTMJ.V87I2.1172

Danny L. Costantini

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引用次数: 2

摘要

分子成像是一个快速发展的领域，旨在开发新的技术和方法，在细胞和分子水平上对生物体中的特定生物过程进行成像。本文综述了几种利用动脉粥样硬化独特生物学特性来检测疾病关键方面的新型成像策略。在这些方法中，针对巨噬细胞活性、蛋白酶活性、细胞凋亡和血管生成进行动脉粥样硬化的体内分子成像已经显示出最大的转化为临床环境的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Molecular Imaging of Atherosclerosis

Molecular imaging is a rapidly evolving field that aims to develop novel technologies and methods to image specific biological processes in the living organism at the cellular and molecular level. This review discusses several novel imaging strategies that exploit the unique biological properties of atherosclerosis to detect key aspects of the disease. Among the approaches, targeting macrophage activity, protease activity, apoptosis and angiogenesis for in vivo molecular imaging of atherosclerosis have demonstrated the greatest potential for translation into the clinical setting.

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来源期刊

University of Toronto Medical Journal MEDICINE, GENERAL & INTERNAL-

CiteScore

0.30

自引率

0.00%

发文量