基于纳米颗粒的心肌梗死后药物输送系统

Minxuan Liu, Chiara Ramponi, Xiaoxue Fan, Xinzhuang Zhang, Liang Cao, Zhenzhong Wang, W. Xiao
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引用次数: 2

摘要

刘敏轩,Chiara Ramponi,范晓雪,张新庄,曹亮,王振忠,肖伟*,江苏康宁医药股份有限公司中药制药工艺新技术国家重点实验室,连云港,222001。*通讯:xw_kanion@163.com收稿日期:2022年10月15日收稿日期:2022年11月2日发布日期:2022年12月21日摘要:心血管疾病(CVD)是全球发病率和死亡率的主要原因。心肌梗死(MI)作为缺血性心脏病最有害的形式之一,需要严格和有力的方法,目前的临床干预措施无法满足。纳米技术在成像、诊断、基因传递和组织工程等方面的临床应用前景广阔,这使得纳米技术成为一种潜在的新型治疗传递方法。这篇综述重点介绍了最近关于使用纳米颗粒(NP)策略的药物递送进展的几项研究报告,以及未来的挑战和机遇。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanoparticle-based Drug Delivery System for Post Myocardial Infarction Management
Review Nanoparticle-based Drug Delivery System for Post Myocardial Infarction Management Minxuan Liu, Chiara Ramponi, Xiaoxue Fan, Xinzhuang Zhang, Liang Cao, Zhenzhong Wang, and Wei Xiao * State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang, 222001, China. * Correspondence: xw_kanion@163.com     Received: 15 October 2022 Accepted: 2 November 2022 Published: 21 December 2022   Abstract: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the world. Myocardial infraction (MI) as one of the most harmful forms of ischaemic heart disease requires rigorous and tempestive approaches which are not met by current clinical interventions. Nanotechnology has developed promising clinical applications for imaging, diagnostic, gene delivery and tissue engineering, which makes this technology a potential candidate for novel therapeutic delivery approach. This review highlights several recent research reports regarding advances in drug delivery using nanoparticle-based (NP) strategies, as well as future challenges and opportunities.
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