不同经期对健康女性肝肾功能的影响

S. Jawad
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引用次数: 0

摘要

背景:月经周期是一个重要的生命节律,受雌二醇、黄体酮、黄体生成素和卵泡刺激水平的相互作用调节,在这个周期中,一些代谢参数与性激素一起波动,因此,本研究旨在探讨健康女性的月经周期是否影响肝肾功能。材料和方法:该研究于2018年10月至2019年1月期间在女子教育学院进行。它涉及30名年龄在18至26岁之间的健康妇女的参与。所有参与者都不吸烟,不使用避孕药或激素。此外,她们自信地提到她们有规律的月经周期(在24到32天之间)。结果:黄体期肝酶(ALT、AST、ALP)水平明显高于卵泡期(P≤0.05)。但两期患者血清尿素和肌酐水平无显著差异。结论:肝功能检查结果受月经周期的影响。在评估肝酶时,考虑到这一点是很重要的。内源性E2对肝酶的潜在有益作用也可能令人感兴趣。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Menstrual Different Phases on Liver-Kidney Functions in Healthy Women
Background: The menstrual cycle is a critical rhythm of life regulated by interactive levels of estradiol, progesterone, luteinizing hormones, and follicular stimulation, during this cycle several metabolic parameters fluctuate in conjunction with sex hormones, therefore, this work was performed to investigate whether the menstrual cycle in healthy women affects the liver and kidney function. Materials and Methods: The study was conducted in the Faculty of Education for girls during the period October 2018–January 2019. It involved the participation of thirty healthy women with age between 18 and 26 years. All participants were non-smokers with no use of contraceptives or hormones. In addition, they confidently mentioned that they had had regular menstrual cycles (between 24 and 32 days). Results: Our findings showed that the liver enzymes (ALT, AST and ALP) levels were higher in the luteal phase than their levels in the follicular phase (P≤ 0.05). However, there were no significant differences in the level of blood urea and serum creatinine between the two phases. Conclusion: It can be concluded that the measurement of liver function test can be affected by the phases of menstrual cycle. It is important to take that into consideration when assessing the liver enzymes. It may also be of interest the potential beneficial effect endogenic E2 on liver enzymes.
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