新型冠状病毒肺炎(COVID-19)过程中破坏性肺炎的发病机制探讨

Q4 Medicine

Pulmonologiya Pub Date : 2023-02-11 DOI:10.18093/0869-0189-2023-33-1-92-101

O. Zaytseva, E. Tolstova, D. Khaspekov, N. V. Tkachenko, N. A. Scholohova, H. Simonovskaya, Т. Y. Belyaeva

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引用次数: 0

摘要

社区获得性肺炎是儿童中一种潜在的严重感染，发病率高，病程严重，预后不良。专家们注意到近年来破坏性形式的发病率有所增加。本文报道1例1岁2个月大的破坏性肺炎患儿，住院于国家预算医疗机构“莫斯科圣弗拉基米尔保健科儿童城临床医院”，并结合目前对该病发病机制的认识进行分析。在2019冠状病毒病大流行期间，肺病学家和儿科外科医生遇到了一种非常规的破坏性肺炎病程。近年来，大量关于急性病毒性间质性肺炎病理生理过程的研究扩大了我们对凝血系统作用的认识。同时，对病理感染过程的临床过程和发展也提出了新的问题。

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On the pathogenesis of destructive pneumonia during COVID-19: a clinical case

Community-acquired pneumonia is a potentially serious infection in children with high morbidity rate, risk of severe course and unfavorable outcomes. Specialists have noted the increased incidence of the destructive forms in the recent years.Aim. To present a clinical case of destructive pneumonia in a 1 year 2 month old child, hospitalized in the State Budgetary Healthcare Institution “Children’s City Clinical Hospital of St. Vladimir Moscow Healthcare Department”, and analyze it in terms of current understanding on the disease pathogenesis.Conclusion. During COVID-19 (COronaVIrus Disease 2019) pandemic, pulmonologists and pediatric surgeons encountered an unconventional course of destructive pneumonia. A large number of studies of pathophysiological processes in acute viral interstitial pneumonias have recently allowed to expand our understanding of the role of coagulation system. At the same time, new questions arose concerning the clinical course and development of the pathological infectious process.

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来源期刊

Pulmonologiya Medicine-Pulmonary and Respiratory Medicine

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： The aim of this journal is to state a scientific position of the Russian Respiratory Society (RRS) on diagnosis and treatment of respiratory diseases based on recent evidence-based clinical trial publications and international consensuses. The most important tasks of the journal are: -improvement proficiency qualifications of respiratory specialists; -education in pulmonology; -prompt publication of original studies on diagnosis and treatment of respiratory diseases; -sharing clinical experience and information about pulmonology service organization in different regions of Russia; -information on current protocols, standards and recommendations of international respiratory societies; -discussion and consequent publication Russian consensus documents and announcement of RRS activities; -publication and comments of regulatory documents of Russian Ministry of Health; -historical review of Russian pulmonology development. The scientific concept of the journal includes publication of current evidence-based studies on respiratory medicine and their discussion with the participation of Russian and foreign experts and development of national consensus documents on respiratory medicine. Russian and foreign respiratory specialists including pneumologists, TB specialists, thoracic surgeons, allergists, clinical immunologists, pediatricians, oncologists, physiologists, and therapeutists are invited to publish article in the journal.