测试含有咖啡级活性炭(咖啡阿拉比卡L.)和维生素E的面部磨砂制剂的抗衰老活性

Q3 Pharmacology, Toxicology and Pharmaceutics
Dara Sukma Ratmelya, Julia Reveny, U. Harahap
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引用次数: 0

摘要

皮肤表面堆积过多的死皮细胞会导致衰老。咖啡渣是咖啡冲泡过程中的副产品。咖啡渣可以在磨砂膏中用作活性炭。本研究的目的是制备和测试添加维生素e的咖啡渣活性炭(Coffea arabica L.)抗衰老磨砂制剂的有效性。材料和方法:研究方法包括将咖啡渣以干燥和活性炭的形式加工,然后配制成浓度为1%的磨砂制剂;2%, 3%含维生素E, 5%不含维生素E和blanc(不含活性炭)。面部磨砂膏制剂的评估包括均匀性测试、稳定性测试(气味、颜色、pH值和稠度)、循环测试、分散测试、粘度测试、离心测试、愉悦测试、刺激测试和有效性测试(水分、毛孔、污渍、皱纹),使用皮肤分析仪对24名志愿者进行面部皮肤测试,每周一次,持续4周。实验数据采用SPSS 22软件进行分析。结果:所有磨砂膏均为膏霜状,呈灰黑色颗粒状,有咖啡香味,均质,室温(20-25℃)保存12周稳定,pH值(5.0-6.0),扩散力5-7 cm,粘度(3760-3996 mPa),离心试验不发生分离,不刺激面部皮肤。hedonic试验结果表明,F3制剂是最优选的制剂。效果试验结果为:湿度增加27%,孔径减少35.8%,污渍减少40%,皱纹减少37.6%。结论:从研究结果可以得出,活性炭咖啡渣(Coffea arabica L.)浓度为3%,维生素E 5%的磨砂制剂是符合制剂评价的配方,并测量了抗衰老的有效性
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Test anti-aging activity in a face scrub preparation that contains coffee-grade active charcoal (Coffea arabica L.) with the addition of vitamin E
Ageing can be caused by accumulating excess dead skin cells on the skin's surface. Coffee grounds are a by-product of the coffee brewing process. Coffee grounds can be used as activated charcoal in face scrub preparations. The purpose of this study was to formulate and test the effectiveness of anti-ageing face scrub preparations of coffee grounds activated charcoal (Coffea arabica L.) with the addition of vitamin E. Material and methods: the research method includes processing coffee grounds in the form of drying and making activated charcoal, then formulating into face scrub preparations with a concentration of 1 %; 2 %, 3 % with vitamin E, 5 % and without vitamin E and blanc (without activated charcoal). Evaluation of face scrub preparations includes homogeneity test, stability test (odour, colour, pH and consistency), cycling test, dispersion test, viscosity test, centrifugation test, hedonic test, irritation test, and effectiveness test (moisture, pores, stains, wrinkles) on facial skin using a skin analyser on 24 volunteers with application to the face once a week for 4 weeks. The experimental data were analysed using the SPSS 22 program. Results: they showed that all face scrub preparations were in the form of cream with grey-black granules, coffee-scented, homogeneous, stable for 12 weeks of storage at room temperature (20-25°C), pH value (5.0-6.0), had a spreading power of 5-7 cm, viscosity (3760-3996 mPa's), no separation occurs in the centrifugation test and does not irritate facial skin. The results of the hedonic test, the most preferred formulation, was the F3 preparation. The effectiveness test results were an increase in humidity of 27 %, a decrease in pore size of 35.8 %, stains of 40 % and wrinkles of 37.6 %. Conclusion: from the results of the study, it can be concluded that the face scrub preparation of activated charcoal coffee grounds (Coffea arabica L.) with a concentration of 3 % and vitamin E 5 % is a formula that meets the evaluation of the preparation and measures the effectiveness of anti-ageing
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来源期刊
ScienceRise: Pharmaceutical Science
ScienceRise: Pharmaceutical Science Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.70
自引率
0.00%
发文量
39
审稿时长
6 weeks
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