在肠梗阻的发展过程中，CXCL1表达上调，导致肠道收缩活性降低

Neurogastroenterology & Motility Pub Date : 2019-11-13 DOI:10.1111/nmo.13757

T. Docsa, D. Bhattarai, Ádám Sipos, C. Wade, C. Cox, K. Uray

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引用次数: 15

摘要

尽管肠梗阻的发展是广泛的，并对患者的预后产生负面影响，但肠梗阻发展的机制尚不清楚。本研究的目的是探讨术后肠梗阻发展中肌源性机制的贡献，以及炎症介导肠平滑肌功能障碍的参与。

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CXCL1 is upregulated during the development of ileus resulting in decreased intestinal contractile activity

Although the development of ileus is widespread and negatively impacts patient outcomes, the mechanism by which ileus develops remains unclear. The purpose of our study was to examine the contribution of myogenic mechanisms to postoperative ileus development and the involvement of inflammation in mediating intestinal smooth muscle dysfunction.

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Neurogastroenterology & Motility

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