颈动脉内膜切除术后早期中风:5年期间的病例系列

C. Manojlović, D. Milošević, N. Budakov, V. Marković, D. Nikolić
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引用次数: 0

摘要

介绍。颈动脉内膜切除术是无症状和有症状的颅外颈动脉病变患者缺血性卒中一级和二级预防的有效手术方法。材料和方法。在本文中,我们分析了在诺维萨德伏伊伏丁那临床中心血管和血管内手术诊所(809例)接受颈动脉狭窄手术的患者(2013年4月至2018年3月)颈动脉内膜切除术后早期卒中的发生率、危险因素、潜在原因和预防措施。结果和讨论。12例患者登记了早期手术卒中,有症状(2.8%)和无症状(1.1%)患者之间无显著差异(优势比- 2,56,95%置信区间- 0.8063至8.1770,标准差为1,596;P = 0,11)。对侧颈动脉闭塞(优势比- 3.1154,95%可信区间- 1.1620至8.3522,p = 0.0239)和无双重抗血小板治疗(优势比- 3.1154,95%可信区间- 1.8537至526.4871;P = 0.0169)为手术卒中的危险因素。颈动脉内膜切除术后围手术期及术后早期卒中多为动脉-动脉血栓栓塞、脑出血及急性颈动脉闭塞所致,发生较少,伴有严重的神经功能缺损。结论。尽管我们的结果与文献数据一致,但额外的手术质量控制措施将进一步降低手术卒中的发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early stroke after carotid endarterectomy : A case series during a 5-year period
Introduction. Carotid endarterectomy is an efficient surgical procedure of primary and secondary prevention of ischemic stroke in asymptomatic and symptomatic patients with extra cranial carotid artery disease. Material and Methods. In this paper we analyzed incidence, risk factors, potential causes and preventive measures for early stroke after carotid endarterectomy in patients (809) who underwent surgery for carotid artery stenosis at the Clinic of Vascular and Endovascular Surgery of the Clinical Center of Vojvodina in Novi Sad during a five year period (April 2013 - March 2018). Results and Discussion. Early operative stroke was registered in 12 patients with no significant difference between symptomatic (2.8%) and asymptomatic (1.1%) patients (odds ratio - 2,56, 95% confidence interval - 0.8063 to 8.1770 standard deviation 1,596; p = 0,11). Contralateral carotid occlusion (odds ratio - 3.1154, 95% confidence interval - 1.1620 to 8.3522, p = 0.0239) and no dual antiplatelet therapy (odds ratio - 3.1154, 95% confidence interval - 1.8537 to 526.4871; p = 0.0169) were pointed out as risk factors for operative stroke. Most of the perioperative and early postoperative strokes after carotid endarterectomy were due to arterial-arterial thromboembolism, intracerebral hemorrhage and acute carotid occlusion that developed rarely and were associated with severe neurological deficit. Conclusion. Even though our results are in agreement with the literature data, additional measures for surgical quality control would further decrease the incidence of operative stroke.
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