糖尿病冠状动脉搭桥术患者的预后

I. Moursi, K. Al Fakharany
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引用次数: 4

摘要

背景糖尿病(DM)被认为是冠状动脉搭桥手术(CABG)的死亡率和发病率的危险因素。研究表明,对冠状动脉手术后的糖尿病患者的结果存在争议。我们研究的目的是评估这组患者的短期预后。方法对2014年1月至2016年1月在埃及Zagazig大学医院行CABG的180例患者进行单中心回顾性研究。1组为糖尿病患者61例(34%),2组为非糖尿病患者119例(66%)。随访期间对住院死亡率、并发症及主要心血管事件进行分析。所有诊断为糖尿病的住院患者HbA1c≥6.5%或空腹血糖(FBG)≥126 mg/dL (7.0 mmol/L)。结果糖尿病组手术死亡率为3% (n = 2),非糖尿病组手术死亡率为1% (n = 1) (p = 0.3)。糖尿病患者的Euro评分可预测较高(1.2 vs 0.84, p = 0.001)。对医院并发症相关危险因素的研究显示,无糖尿病是医院并发症的保护因素,但统计上不显著。2年随访期间,糖尿病组和非糖尿病组的主要心血管事件发生率分别为(12/50)24%和(16/93)17% (p = 0.43)。结论改善对糖尿病患者的管理,可使冠脉搭桥术后的手术死亡率达到可接受的水平,短期随访期间并发症和事件的发生率降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prognosis of diabetic coronary artery bypass graft surgery patients

Background

Diabetes mellitus (DM) is considered as mortality and morbidity risk factor for coronary artery bypass graft surgery (CABG). Studies revealed that there are controversies concerning the results of a post coronary surgery diabetic patients. The aim of our study was the evaluation of the short-term outcomes in this group of patients.

Methods

This was a single-center retrospective study of 180 patients that were subjected to CABG between January 2014 and January 2016 in Zagazig University Hospital, Zagazig, Egypt. Sixty-one patients (34%) were diabetic (group I) and 119 patients (66%) were non-diabetic (group II). During follow-up period the hospital mortality, complications and major cardiovascular events were analyzed. All patients admitted with a diagnosis of diabetes had an HbA1c ≥ 6.5% or fasting blood glucose (FBG) ≥ 126 mg/dL (7.0 mmol/L).

Results

Operative mortality was 3% (n = 2) in the diabetic group and 1% (n = 1) in non-diabetic patients (p = 0.3). Euro score was predictably higher in diabetic patients (1.2 vs 0.84, p = 0.001). The study of the risk factors associated with hospital complications revealed that the absence of diabetes was a protective factor for hospital complications but statistically insignificant. The rate of major cardiovascular events at 2 years period of follow-up in diabetic and non-diabetic groups was (12/50) 24% and (16/93)17%, respectively (p = 0.43).

Conclusions

The improvement in management of DM patients leads to acceptable operative mortality post-CABG and decrease the incidence of complications and events in the short-term follow-up period.

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