快速系统指南对疑似癫痫患儿的影响

L.R. Morales-Mancías, S. Vázquez-Fuentes, A.C. Cantú-Salinas, L. de León-Flores, B.E. Chávez-Luévanos, H. Villarreal-Velázquez
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引用次数: 0

摘要

目的对疑似癫痫患儿采用系统的快速诊断指南,提高癫痫病因诊断率(根据2010年ILAE分类)。方法采用双视角队列研究。以16岁以下疑似癫痫患者为研究对象,前瞻性组采用系统的快速指南,后对两组进行比较。这是一个方便样本,两组的研究期限都是一年。结果前瞻性组120例,回顾性组71例。比较不同病因组的癫痫诊断,在前瞻性组(仅门诊患者)中,3.3%为不明原因癫痫,55%为遗传原因癫痫,36.7%为结构/代谢原因癫痫,5%为非癫痫本身。与此同时,在回顾性组中,52.1%患有不明原因癫痫,11.3%患有遗传原因癫痫,36.6%患有结构/代谢原因癫痫(p <0.001)。结论与其他同类研究相比,癫痫的病因率有所上升。采用提出的系统快速指南,儿科患者癫痫病因定义的百分比增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of a rapid systemic guide on pediatric patients with suspicion of epilepsy

Objectives

Increase the percentage of etiological diagnosis of epilepsy (according to the classification by the 2010 ILAE) using a systematic quick guide for pediatric patients with suspected epilepsy.

Methods

Ambispective cohort study. Patients under 16 years old with suspected epilepsy were studied, and a systematic quick guide was applied to the prospective group, and later the two groups were compared. It was a convenience sample, with a study period of one year for both groups.

Results

The prospective group was 120 patients and the retrospective group 71 patients. Comparing the epileptic diagnosis by etiology groups, in the prospective group (only outpatient patients), 3.3% had epilepsy of an unknown cause, 55% had epilepsy of a genetic cause, 36.7% had epilepsy of a structural/metabolic cause, and 5% had conditions that are not epilepsy itself. Meanwhile in the retrospective group, 52.1% had epilepsy of an unknown cause, 11.3% had epilepsy of a genetic cause, and 36.6% had epilepsy of a structural/metabolic cause (p < 0.001).

Conclusions

Compared to other similar studies, the etiological percentages of epilepsy increased. Using the systematic quick guide proposed, the percentage of etiological definitions of epilepsy was increased in pediatric patients.

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