各种浆细胞瘤的诊断和治疗特点

V. Voytsekhovskiy, A. Grigorenko, T. Esenina, S. N. Roshchin, E. Filatova, N. Fedorova, V. A. Krivutsa, Ya. D. Zueva, M. V. Sayapina
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引用次数: 0

摘要

的目标。浆细胞瘤的临床病例论证,既有孤立性的,也有多发性骨髓瘤的表现之一。材料和方法。简要回顾了骨和髓外浆细胞瘤的诊断和临床观察各种肿瘤的选择,从作者的个人实践提出。结果。两个临床观察孤立浆细胞瘤的初步诊断提出。一例为骨肿瘤,另一例为髓外肿瘤。在这两次观察中,随后注意到这一过程的普遍化。本文还报告了3例原发性多发性骨髓瘤伴浆细胞瘤发展的临床病例。在两个病例中,有骨髓病变,在一个-多灶形式的疾病。在两种情况下,诊断为多发性骨髓瘤的非分泌性变异。分析其诊断和治疗特点。结论。在局灶性浆细胞瘤的诊断中(没有对骨髓和分泌物的损害),组织学和免疫组织化学研究起主导作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Features of diagnostics and treatment of various plasmacytoma options
Aim. Demonstration of clinical cases of plasmacytoma, both solitary and one of the manifestations of multiple myeloma. Materials and methods. A brief literature review on the diagnosis of bone and extramedullary plasmacytoma and clinical observations of various tumor options from the personal practice of the authors is presented. Results. Two clinical observations of the primary diagnosis of solitary plasmacytoma are presented. In one case, there was a bone tumor, in the other − an extramedullary tumor. In both observations, a generalization of the process was subsequently noted. Three clinical cases of primary diagnosis of multiple myeloma accompanied by the development of plasmacytoma are also presented. In two cases, there was a lesion of the bone marrow, in one – a multiple-focal form of the disease. In two situations, a non-secreting variant of multiple myeloma was diagnosed. The features of diagnosis and treatment were analyzed. Conclusion. In the diagnosis of focal forms of plasmacytoma (without lesions to the bone marrow and secretion), the leading role belongs to histological and immunohistochemical studies. 
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