{"title":"新N′-(3-羟基- 3,4 -二氢喹啉-2-羰基)-N-苯基氨基甲酸衍生物的合成及抗结核活性","authors":"Shripad Potadar, R. Kotnal","doi":"10.18231/j.ijpca.2020.010","DOIUrl":null,"url":null,"abstract":"A new series new N’-(3-hydroxy-3,4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid\nderivatives were designed and synthesized. The newly synthesized compounds were evaluated for\ntheir anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis\nand spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that;\nsynthesized compounds showed the good to moderate anti-tb activities.\n\nKeywords: Quinoxaline, Orthophenylenediamine, Alloxane and antimycobacterial.","PeriodicalId":14317,"journal":{"name":"International Journal of Pharmaceutical Chemistry","volume":"530 1","pages":"66-68"},"PeriodicalIF":0.0000,"publicationDate":"2020-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis and Anti tubercular activity of some new N’-(3-hydroxy-3, 4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid derivatives\",\"authors\":\"Shripad Potadar, R. Kotnal\",\"doi\":\"10.18231/j.ijpca.2020.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A new series new N’-(3-hydroxy-3,4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid\\nderivatives were designed and synthesized. The newly synthesized compounds were evaluated for\\ntheir anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis\\nand spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that;\\nsynthesized compounds showed the good to moderate anti-tb activities.\\n\\nKeywords: Quinoxaline, Orthophenylenediamine, Alloxane and antimycobacterial.\",\"PeriodicalId\":14317,\"journal\":{\"name\":\"International Journal of Pharmaceutical Chemistry\",\"volume\":\"530 1\",\"pages\":\"66-68\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Pharmaceutical Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijpca.2020.010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmaceutical Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijpca.2020.010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Synthesis and Anti tubercular activity of some new N’-(3-hydroxy-3, 4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid derivatives
A new series new N’-(3-hydroxy-3,4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid
derivatives were designed and synthesized. The newly synthesized compounds were evaluated for
their anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis
and spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that;
synthesized compounds showed the good to moderate anti-tb activities.
Keywords: Quinoxaline, Orthophenylenediamine, Alloxane and antimycobacterial.
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