囊性纤维化儿童支气管肺和肠道的生理和微生物学特征

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引用次数: 0

摘要

粘液粘滞症治疗措施的一个重要组成部分是确定呼吸系统的功能状态,与支气管肺部慢性微生物炎症过程中伴随的机会性感染作斗争。在抵抗力降低的情况下,儿童的9例患者(47.4%)-念珠菌属真菌。2例(10.5%)患者检出非典型埃希菌。其中1例患者检出溶血性大肠杆菌。患者粪便中未检出致病性肠杆菌和葡萄球菌。4例(21%)患者因感染coseri、C. freundii和K.pneumonia被分离。首次诊断黏液性病变组2例(10.5%)患者肠道菌群状态基本在正常范围内。17例患者(89.5%)出现术后生态失调。根据微生物学研究结果,黏液性痰患者肠道的内源性定植尚未得到证实。100%的患者有脂肪漏;2例患者有脂肪漏合并造物漏。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The physiological and microbiological characteristics of bronchopulmonary and intestinal tracts in children with cystic fibrosis
An important component of therapeutic measures for mucoviscidose is the determination of the functional state of the respiratory system, the fight against an opportunistic infection which accompanies the course of the chronic microbial-inflammatory process in the bronchopulmonary tract. Under conditions of reduced resistance to the child’s 9 patients (47,4 %) – fungi of the genus Candida. In 2 patients (10,5 %) Escherichia with atypical properties was found. Hemolytic E. coli were detected in one of the patients. The pathogenic enterobacteria and staphylococcus were not detected in the feces of any patient. 4 patients (21 %) were isolated because of S. coseri, C. freundii and K.pneumonia. In 2 patients (10,5 %) from the group “first diagnosed mucoviscidose” the state of the intestinal microflora was almost within the normal range. In 17 patient (89,5 %) postmedical dysbiosis was indicated. According to the results of microbiological studies, the endogenous colonization of the intestines of patients with mucoviscidose sputum has not been confirmed. One hundred percent of patients had steatorrhea; two patients had steatorrhea combined with creatorrhea.
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