{"title":"肿瘤化疗药物诱导的红细胞毒性。渗透脆弱性和血红蛋白生成的体外研究。","authors":"R. Barr, A. Davidson, L. K. Jung, K. R. Mohan Pai","doi":"10.1111/J.1600-0609.1981.TB01415.X","DOIUrl":null,"url":null,"abstract":"Increased osmotic fragility and methaemoglobin generation in vitro have resulted from the exposure of normal human erythrocytes to numerous cancer chemotherapeutic agents. These findings offer a possible explanation for the earlier, consistent clinical observation of the rapid development of anaemia, during consolidation therapy, in children with acute lymphoblastic leukaemia in remission.","PeriodicalId":21489,"journal":{"name":"Scandinavian journal of haematology","volume":"113 1","pages":"363-8"},"PeriodicalIF":0.0000,"publicationDate":"2009-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":"{\"title\":\"Erythrocytotoxicity induced by cancer chemotherapeutic agents. In vitro studies of osmotic fragility and methaemoglobin generation.\",\"authors\":\"R. Barr, A. Davidson, L. K. Jung, K. R. Mohan Pai\",\"doi\":\"10.1111/J.1600-0609.1981.TB01415.X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Increased osmotic fragility and methaemoglobin generation in vitro have resulted from the exposure of normal human erythrocytes to numerous cancer chemotherapeutic agents. These findings offer a possible explanation for the earlier, consistent clinical observation of the rapid development of anaemia, during consolidation therapy, in children with acute lymphoblastic leukaemia in remission.\",\"PeriodicalId\":21489,\"journal\":{\"name\":\"Scandinavian journal of haematology\",\"volume\":\"113 1\",\"pages\":\"363-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-04-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Scandinavian journal of haematology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/J.1600-0609.1981.TB01415.X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian journal of haematology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/J.1600-0609.1981.TB01415.X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Erythrocytotoxicity induced by cancer chemotherapeutic agents. In vitro studies of osmotic fragility and methaemoglobin generation.
Increased osmotic fragility and methaemoglobin generation in vitro have resulted from the exposure of normal human erythrocytes to numerous cancer chemotherapeutic agents. These findings offer a possible explanation for the earlier, consistent clinical observation of the rapid development of anaemia, during consolidation therapy, in children with acute lymphoblastic leukaemia in remission.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
