生理盐水/碘置换用于体外组织成分测量的x射线成像技术

M. Moreau, D. Holdsworth, J. Dunmore-Buyze, A. Fenster
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引用次数: 0

摘要

一种体外放射成像技术已经发展到研究动脉标本的组成,量化钙化和软组织成分。在作者的新方法中,将幻体浸泡在盐水浴中获得平面x线片:(a)使用45千伏的频谱,没有添加过滤;(b)使用100千伏频谱的碘浴,添加12.5 mm Al过滤。然后将这些x线照片数字化,并使用从Lucite图像和骨等效阶跃楔图像中获得的校准数据转换为骨等效图像和Lucite图像。这些图像的厚度测量结果显示,骨等效图像的平均精度为/spl plusmn/300 /spl mu/m, Lucite图像的平均精度为/spl plusmn/80 /spl mu/m。骨当量图像和Lucite图像的厚度测量精度(一个标准差)分别为200 /spl mu/m和/spl plusmn/150 /spl mu/m。虽然骨等效厚度测量的准确度和精度不如双能x射线成像,但Lucite厚度测量的准确度和精度要好得多。Lucite厚度测量的高精度和精密度使该技术成为双能放射照相(具有骨等效厚度测量的高精度和精密度)的很好的补充,用于研究切除动脉标本的物理性质。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
X-ray imaging technique for in vitro tissue composition measurements using saline/iodine displacement
An in vitro radiographic technique has been developed to study the composition of arterial specimens, quantifying both the calcified and soft tissue components. In the authors' new method, planar radiographs of a phantom were obtained when the phantom was immersed in: (a) a saline bath using a 45-kV, spectrum with no added filtration; and, (b) an iodine bath using a 100-kV, spectrum with 12.5 mm Al added filtration. These radiographs were then digitized and converted into bone-equivalent and Lucite images using calibration data obtained from images of Lucite and bone-equivalent step wedges. Thickness measurements from these images yielded average accuracies of /spl plusmn/300 /spl mu/m for the bone-equivalent image, and /spl plusmn/80 /spl mu/m for the Lucite image. The precision (one standard deviation) of the thickness measurements was 200 /spl mu/m and /spl plusmn/150 /spl mu/m for the bone-equivalent and the Lucite images respectively. Although the accuracy and precision of bone-equivalent thickness measurements were not as good as those obtained with dual-energy X-ray imaging, the accuracy and precision of the Lucite thickness measurements are shown to be much better. The high accuracy and precision of the Lucite thickness measurements make this technique a very good complement to dual-energy radiography (with its high accuracy and precision of bone-equivalent thickness measurement) to study the physical properties of excised arterial specimens.
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