{"title":"一些取代羟基三氮杂烯的合成及其神经药理作用","authors":"L. Chauhan, C. Jain, R. Chauhan, A. Goswami","doi":"10.1234/JGPT.V3I6.397","DOIUrl":null,"url":null,"abstract":"Hydroxytriazene compounds (HT) were synthesized and the purity of each hydroxytriazene was checked by physical characteristics and elemental analysis. The synthesized hydroxytriazenes were studied on some neuropharmacological paradigms on mice like behavior, locomotion, sleep, and convulsions using standard procedures. The hydroxytriazenes exhibited reduced alertness, reduced spontaneous locomotion activity and potentiated the pentobarbitone induced sleep. Conclusively the compounds showed CNS depressant effects.","PeriodicalId":15889,"journal":{"name":"Journal of Global Pharma Technology","volume":"92 1","pages":"9-14"},"PeriodicalIF":0.0000,"publicationDate":"2011-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"SYNTHESIS AND NEUROPHARMACOLOGICAL EFFECTS OF SOME SUBSTITUTED HYDROXYTRIAZENES\",\"authors\":\"L. Chauhan, C. Jain, R. Chauhan, A. Goswami\",\"doi\":\"10.1234/JGPT.V3I6.397\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hydroxytriazene compounds (HT) were synthesized and the purity of each hydroxytriazene was checked by physical characteristics and elemental analysis. The synthesized hydroxytriazenes were studied on some neuropharmacological paradigms on mice like behavior, locomotion, sleep, and convulsions using standard procedures. The hydroxytriazenes exhibited reduced alertness, reduced spontaneous locomotion activity and potentiated the pentobarbitone induced sleep. Conclusively the compounds showed CNS depressant effects.\",\"PeriodicalId\":15889,\"journal\":{\"name\":\"Journal of Global Pharma Technology\",\"volume\":\"92 1\",\"pages\":\"9-14\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-03-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Global Pharma Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1234/JGPT.V3I6.397\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Global Pharma Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1234/JGPT.V3I6.397","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SYNTHESIS AND NEUROPHARMACOLOGICAL EFFECTS OF SOME SUBSTITUTED HYDROXYTRIAZENES
Hydroxytriazene compounds (HT) were synthesized and the purity of each hydroxytriazene was checked by physical characteristics and elemental analysis. The synthesized hydroxytriazenes were studied on some neuropharmacological paradigms on mice like behavior, locomotion, sleep, and convulsions using standard procedures. The hydroxytriazenes exhibited reduced alertness, reduced spontaneous locomotion activity and potentiated the pentobarbitone induced sleep. Conclusively the compounds showed CNS depressant effects.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
