甲状腺切除术后甲状腺功能减退的预测:生化和病理分析。

Abhinav Rathi, D. Sharma, B. Prasad
{"title":"甲状腺切除术后甲状腺功能减退的预测:生化和病理分析。","authors":"Abhinav Rathi, D. Sharma, B. Prasad","doi":"10.9790/0853-1606116163","DOIUrl":null,"url":null,"abstract":"The possibility of postsurgical hypothyroidism after hemithyroidectomy is an underappreciated complication . We intended to evaluate the incidence of development of hypothyroidism after hemithyroidectomy and to analyze the relationship of posthemithyroidectomy hypothyroidism with preoperative biochemical parameters(preoperative TSH,Thyroid antibody levels) and postoperative histopathological findings. From November 2010 to May 2011, 60 cases of hemithyroidectomized patients were analyzed. Postoperative hypothyroidism developed in 19 patients(31.66%). Preoperative TSH value was significantly higher in the hypothyroid group (2.68 μIU/ml) compared to the euthyroid group (1.39 μIU/ml). Elevated thyroid antibody(TAA) levels were observed in 53% of patients developing postoperative hypothyroidism as compared to 12% of patients who remain euthyroid (p = 0.00077) . Moreover, patients with a higher grade of lymphocytic infiltration were found to have a higher probability of developing hypothyroidism. In addition, our findings support the recommendation for regular serum TSH follow-up at least for 6 months after hemithyroidectomy.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Prediction of Hypothyroidism after Hemithyroidectomy: A Biochemical and Pathological Analysis.\",\"authors\":\"Abhinav Rathi, D. Sharma, B. Prasad\",\"doi\":\"10.9790/0853-1606116163\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The possibility of postsurgical hypothyroidism after hemithyroidectomy is an underappreciated complication . We intended to evaluate the incidence of development of hypothyroidism after hemithyroidectomy and to analyze the relationship of posthemithyroidectomy hypothyroidism with preoperative biochemical parameters(preoperative TSH,Thyroid antibody levels) and postoperative histopathological findings. From November 2010 to May 2011, 60 cases of hemithyroidectomized patients were analyzed. Postoperative hypothyroidism developed in 19 patients(31.66%). Preoperative TSH value was significantly higher in the hypothyroid group (2.68 μIU/ml) compared to the euthyroid group (1.39 μIU/ml). Elevated thyroid antibody(TAA) levels were observed in 53% of patients developing postoperative hypothyroidism as compared to 12% of patients who remain euthyroid (p = 0.00077) . Moreover, patients with a higher grade of lymphocytic infiltration were found to have a higher probability of developing hypothyroidism. In addition, our findings support the recommendation for regular serum TSH follow-up at least for 6 months after hemithyroidectomy.\",\"PeriodicalId\":14489,\"journal\":{\"name\":\"IOSR Journal of Dental and Medical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IOSR Journal of Dental and Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9790/0853-1606116163\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IOSR Journal of Dental and Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9790/0853-1606116163","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4

摘要

甲状腺切除术后甲状腺功能减退的可能性是一个未被重视的并发症。我们旨在评估甲状腺切除术后甲状腺功能减退的发生率,并分析甲状腺切除术后甲状腺功能减退与术前生化参数(术前TSH、甲状腺抗体水平)和术后组织病理学结果的关系。本文对2010年11月至2011年5月60例甲状腺切除术患者进行了分析。术后发生甲状腺功能减退19例(31.66%)。甲状腺功能减退组术前TSH值(2.68 μIU/ml)明显高于甲状腺功能正常组(1.39 μIU/ml)。53%的术后甲状腺功能减退患者甲状腺抗体(TAA)水平升高,而12%的术后甲状腺功能正常患者甲状腺抗体水平升高(p = 0.00077)。此外,淋巴细胞浸润程度越高的患者发生甲状腺功能减退的可能性越大。此外,我们的研究结果支持在甲状腺切除术后进行至少6个月的常规血清TSH随访的建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prediction of Hypothyroidism after Hemithyroidectomy: A Biochemical and Pathological Analysis.
The possibility of postsurgical hypothyroidism after hemithyroidectomy is an underappreciated complication . We intended to evaluate the incidence of development of hypothyroidism after hemithyroidectomy and to analyze the relationship of posthemithyroidectomy hypothyroidism with preoperative biochemical parameters(preoperative TSH,Thyroid antibody levels) and postoperative histopathological findings. From November 2010 to May 2011, 60 cases of hemithyroidectomized patients were analyzed. Postoperative hypothyroidism developed in 19 patients(31.66%). Preoperative TSH value was significantly higher in the hypothyroid group (2.68 μIU/ml) compared to the euthyroid group (1.39 μIU/ml). Elevated thyroid antibody(TAA) levels were observed in 53% of patients developing postoperative hypothyroidism as compared to 12% of patients who remain euthyroid (p = 0.00077) . Moreover, patients with a higher grade of lymphocytic infiltration were found to have a higher probability of developing hypothyroidism. In addition, our findings support the recommendation for regular serum TSH follow-up at least for 6 months after hemithyroidectomy.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信