Elena-Beatriz Bermúdez-Bejarano, A. Martins, A. Lorenzo, Ana Castro, Alejandro López
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Implications of endodontic treatment in chemo-osteonecrosis of the maxillary jaw due to bisphosphonates. An updated review
Introduction: Chemo-osteonecrosis of the jaw can be caused by the pharmacodynamics of bisphosphonates and periapical-pulp physiopathology. Therefore, the objective of this study was to carry out a bibliographic review on endodontic treatment and chemo-osteonecrosis of the jaw and its recommendations. Materials and Methods: An electronic systematic review has been prepared in the PubMed and manual verification from 2005 to 2020, according to the 2020 Prism Guidelines and using inclusion and exclusion criteria, under the terms: “Bisphosphonate AND root canal therapy” and “Bisphosphonate associated osteonecrosis of the jaw AND endodontics.” Results: The 22 selected articles were divided into two differentiated blocks. The first one includes endodontic treatment in patients with bisphosphonate therapy and its relationship with maxillary chemo-osteonecrosis. The second includes recommendations to be followed in patients on bisphosphonate and root canal therapy. Conclusions: Patients who were administered intravenous or intraoral bisphosphonates for more than 4 years with associated risk factors are more predisposed to chemo-osteonecrosis of the jaw. Endodontics is safe compared to other traumatic procedures.
期刊介绍:
Vision SEJ aims to be one of the foremost worldwide periodical on Endodontics, dedicated to the promotion of research, post-graduate training and further education in Endodontics. Mission Statement To serve as a medium for continued Endodontic education and qualitative scientific publications on clinical trials, basic science related to the biological aspects of Endodontics, basic science related to Endodontic techniques as well as dental trauma that will ultimately improve the Endodontic research and patient’s health. Scope In this journal, Endodontists, Endodontic postgraduate students and general dentists, can learn about new concepts in root canal treatment and the latest advances in techniques and instrumentation that help them keep pace with rapid changes in this field. Aims and Objectives To publish cut edge peer-review original articles, case reports, letters to the editor, editorials, review articles, commentaries, and innovations that will impact on Endodontics. To enhance exchange of ideas/information relating to Endodontics and interaction among stakeholders. To encourage networking and partnership between individuals, government and non-governmental organizations for the provision of quality health care. To advocate for training, workshops, seminars, scientific manuscript writing conferences that will advance publishing culture.