兜售干细胞——我们见过敌人,他就是我们自己

A. Caplan, A. Tsou
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引用次数: 1

摘要

在潜在的万灵药中,干细胞疗法在公众的想象中有着悠久而传奇的存在。干细胞疗法被广泛认为是治疗其他无法治愈的疾病的最有希望的途径之一,已被用作治疗许多血液疾病的关键因素,并取得了巨大成功(Kline 2006)。随着成人干细胞、胚胎干细胞、诱导干细胞、胎儿干细胞和克隆干细胞的新形式的出现,那些患有其他不治之症的人对其临床应用的兴趣也相应增加。可悲的是,患有晚期和慢性疾病的患者可能被利用的方法数量也在迅速增长(Murdoch and Scott 2010;Caplan和Levine 2010)。与许多技术创新一样,互联网的广泛使用也被证明是一把双刃剑。患者现在有能力充分了解现有的临床试验和正在进行的涉及新型干细胞的研究。矛盾的是,在线信息也为不诚实的干细胞“治疗”供应商创造了前所未有的机会,传播错误信息,利用慢性病和绝症患者的绝望。在这样的环境下,仅仅警告患者警惕潜在的医疗贩子在道德上是不够的(Caplan和Levine 2010)。医学研究日益复杂的性质,以及潜在患者及其家属可获得的大量信息,对试图辨别事实与虚构的患者构成了真正的障碍。潜在患者可能无法判断各种干预措施的治疗潜力,或者受到未经证实的疗效声明的过度影响。潜在的患者很容易被不了解最新的“研究”,被庸医和骗子欺骗,或者对那些兜售干细胞“疗法”的人所使用的生物材料的不可靠性缺乏了解,这些生物材料的唯一目的是中饱私囊。这些挑战仍然没有得到足够的承认,更不用说得到充分的回应了。然而,在寻求形成
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Touting Stem Cells—We Have Seen the Enemy and He Is Us
In the pantheon of potential medical cure-alls, stem-cell therapy has enjoyed a long and storied existence in the public imagination. Widely believed to be one of the most promising avenues for treatment of otherwise untreatable diseases, stem-cell therapy has been used as a key element in the treatment of many blood disorders with great success (Kline 2006). As newer forms of adult, embryonic, induced, fetal, and cloned stem cells appear, the interest among those afflicted with otherwise incurable ailments in their clinical application grows accordingly. Sadly, the number of ways in which patients with terminal and chronic diseases may be potentially exploited is growing rapidly as well (Murdoch and Scott 2010; Caplan and Levine 2010). Like many technological innovations, the widespread availability of the Internet has proved characteristically double-edged. Patients now possess the capability to be well informed about available clinical trials and ongoing research involving novel forms of stem cells. Paradoxically, online information has also created unprecedented opportunities for disingenuous vendors of stem cell “treatments” to disseminate misinformation and exploit the desperation of the chronically and terminally ill. In such a climate, simply warning patients to be wary of potential medical hucksters is ethically inadequate (Caplan and Levine 2010). The increasingly complex nature of medical research and sheer volume of information available to prospective patients and their families represent genuine obstacles for patients trying to discern fact from fiction. Would-be patients may be ill-equipped to judge the therapeutic potential of various interventions or be unduly influenced by unsubstantiated claims of efficacy. Prospective patients are highly susceptible to being ill-informed about the latest “research,” lied to by quacks and charlatans, or deficient in their knowledge about the unreliability of biological materials being used by those touting stem cell “therapies” with the sole aim of lining their pockets. These challenges remain insufficiently acknowledged, much less garnering adequate responses. However, in seeking to form
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