蜂蜜对心理应激动物正畸牙齿运动和破骨细胞活性的影响

Reem Abid
{"title":"蜂蜜对心理应激动物正畸牙齿运动和破骨细胞活性的影响","authors":"Reem Abid","doi":"10.47489/pszmc-815354-46-50","DOIUrl":null,"url":null,"abstract":"Introduction: Orthodontics is a clinical specialty in dentistry related to the correction of dentofacial deformities. Psychological stress factors delay Orthodontic tooth movement (OTM). Honey can be considered a useful and harmless natural product to reduce stress levels, hence improves the efficacy of OTM.\n\nAims & Objectives: To compare the differences in the rate of tooth movement and osteoclastic activity between control, psychologically stressed and honey treated psychologically stressed groups after 1 week of orthodontic force application in an animal model.\n\nPlace and duration of study: This experimental study was conducted at the animal research laboratory and Histopathology Department of Post Graduate Medical Institute (PGMI), Lahore, Pakistan, from April 2019 to June 2020.\n\nMaterial & Methods: Thirty-six Sprague Dawley rats were randomly divided into A, B and C groups. Psychological Stress was induced in group A (PS group) while Honey was given orally as a therapeutic agent along with induction of psychological stress in group B (PSH group), and group C was the Control Group. Statistical analyses were performed using SPSS version 24 software. The quantitative variables were the orthodontic tooth movement, the osteoclast count, and the expression of RANKL. One-way ANOVA was applied to calculate the mean difference and Post hoc Tukey test applied for multiple comparisons among the groups. A p-value ? 0.05 was considered statistically significant in all 3 groups.\n\nResults: There was a significant difference (p-value <0.05) between control and experimental groups in the orthodontic tooth movement and levels of RANKL, however, there was no significant difference between PS and PSH groups.\n\nConclusion: Psychological stress delays orthodontic tooth movement by causing a reduction in its rate and osteoclastic activity and honey has no significant correlation with lowering stress levels, hence does not improve orthodontic tooth movement efficiency.","PeriodicalId":20500,"journal":{"name":"Proceedings of Shaikh Zayed Medical Complex Lahore","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of Honey on Orthodontic Tooth Movement and Osteoclastic Activity in Psychologically Stressed Animals\",\"authors\":\"Reem Abid\",\"doi\":\"10.47489/pszmc-815354-46-50\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Orthodontics is a clinical specialty in dentistry related to the correction of dentofacial deformities. Psychological stress factors delay Orthodontic tooth movement (OTM). Honey can be considered a useful and harmless natural product to reduce stress levels, hence improves the efficacy of OTM.\\n\\nAims & Objectives: To compare the differences in the rate of tooth movement and osteoclastic activity between control, psychologically stressed and honey treated psychologically stressed groups after 1 week of orthodontic force application in an animal model.\\n\\nPlace and duration of study: This experimental study was conducted at the animal research laboratory and Histopathology Department of Post Graduate Medical Institute (PGMI), Lahore, Pakistan, from April 2019 to June 2020.\\n\\nMaterial & Methods: Thirty-six Sprague Dawley rats were randomly divided into A, B and C groups. Psychological Stress was induced in group A (PS group) while Honey was given orally as a therapeutic agent along with induction of psychological stress in group B (PSH group), and group C was the Control Group. Statistical analyses were performed using SPSS version 24 software. The quantitative variables were the orthodontic tooth movement, the osteoclast count, and the expression of RANKL. One-way ANOVA was applied to calculate the mean difference and Post hoc Tukey test applied for multiple comparisons among the groups. A p-value ? 0.05 was considered statistically significant in all 3 groups.\\n\\nResults: There was a significant difference (p-value <0.05) between control and experimental groups in the orthodontic tooth movement and levels of RANKL, however, there was no significant difference between PS and PSH groups.\\n\\nConclusion: Psychological stress delays orthodontic tooth movement by causing a reduction in its rate and osteoclastic activity and honey has no significant correlation with lowering stress levels, hence does not improve orthodontic tooth movement efficiency.\",\"PeriodicalId\":20500,\"journal\":{\"name\":\"Proceedings of Shaikh Zayed Medical Complex Lahore\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-11-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of Shaikh Zayed Medical Complex Lahore\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47489/pszmc-815354-46-50\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of Shaikh Zayed Medical Complex Lahore","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47489/pszmc-815354-46-50","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

口腔正畸是一门与牙面畸形矫正有关的牙科临床专业。心理应激因素影响正畸牙齿运动。蜂蜜可以被认为是一种有用和无害的天然产品,以减少压力水平,因此提高OTM的功效。目的:在动物模型中比较正常组、心理应激组和蜂蜜治疗心理应激组在正畸力施加1周后牙齿移动率和破骨细胞活性的差异。研究地点和时间:本实验研究于2019年4月至2020年6月在巴基斯坦拉合尔研究生医学研究所(PGMI)动物研究实验室和组织病理学部进行。材料与方法:36只Sprague Dawley大鼠随机分为A、B、C组。A组(PS组)诱导心理应激,B组(PSH组)在诱导心理应激的同时口服蜂蜜作为治疗剂,C组为对照组。采用SPSS 24版软件进行统计分析。定量变量为正畸牙移动、破骨细胞计数、RANKL表达。组间多组比较采用单因素方差分析,组间多组比较采用事后Tukey检验。p值?3组差异均以0.05为差异有统计学意义。结果:对照组与实验组正畸牙移动及RANKL水平差异有统计学意义(p值<0.05),而PS组与PSH组之间差异无统计学意义(p值<0.05)。结论:心理应激导致正畸牙齿移动速度和破骨细胞活性降低,从而延缓正畸牙齿移动,蜂蜜与降低应激水平无显著相关性,因此不能提高正畸牙齿移动效率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Honey on Orthodontic Tooth Movement and Osteoclastic Activity in Psychologically Stressed Animals
Introduction: Orthodontics is a clinical specialty in dentistry related to the correction of dentofacial deformities. Psychological stress factors delay Orthodontic tooth movement (OTM). Honey can be considered a useful and harmless natural product to reduce stress levels, hence improves the efficacy of OTM. Aims & Objectives: To compare the differences in the rate of tooth movement and osteoclastic activity between control, psychologically stressed and honey treated psychologically stressed groups after 1 week of orthodontic force application in an animal model. Place and duration of study: This experimental study was conducted at the animal research laboratory and Histopathology Department of Post Graduate Medical Institute (PGMI), Lahore, Pakistan, from April 2019 to June 2020. Material & Methods: Thirty-six Sprague Dawley rats were randomly divided into A, B and C groups. Psychological Stress was induced in group A (PS group) while Honey was given orally as a therapeutic agent along with induction of psychological stress in group B (PSH group), and group C was the Control Group. Statistical analyses were performed using SPSS version 24 software. The quantitative variables were the orthodontic tooth movement, the osteoclast count, and the expression of RANKL. One-way ANOVA was applied to calculate the mean difference and Post hoc Tukey test applied for multiple comparisons among the groups. A p-value ? 0.05 was considered statistically significant in all 3 groups. Results: There was a significant difference (p-value <0.05) between control and experimental groups in the orthodontic tooth movement and levels of RANKL, however, there was no significant difference between PS and PSH groups. Conclusion: Psychological stress delays orthodontic tooth movement by causing a reduction in its rate and osteoclastic activity and honey has no significant correlation with lowering stress levels, hence does not improve orthodontic tooth movement efficiency.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信