特发性颅内高压的病程及视觉预后的预测因素

IF 0.8 Q4 CLINICAL NEUROLOGY

Neuro-Ophthalmology Pub Date : 2021-10-13 DOI:10.1080/01658107.2021.1984540

R. Behbehani, Abdullah Ali, Ashraf Al-Moosa

{"title":"特发性颅内高压的病程及视觉预后的预测因素","authors":"R. Behbehani, Abdullah Ali, Ashraf Al-Moosa","doi":"10.1080/01658107.2021.1984540","DOIUrl":null,"url":null,"abstract":"ABSTRACT Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. There are few studies in the literature about the visual outcome of IIH. We have reviewed the record of 76 patients with IIH according to the modified Dandy criteria. There was a significant improvement in the Humphrey 24-2 mean deviation (MD) in the study eyes (worse affected eye at presentation) in both the medically treated group (+2.0 dB; from −5.60 dB at baseline to −3.60 dB at final follow-up, p < .01) and in the fellow eyes in the medically treated group (+1.70 dB, from −4.40 dB at baseline to −2.74 dB at final follow-up, p < .01). Higher papilloedema grade (beta −0.66, p < .001) and age (p < .02) were inversely correlated with the final visual field MD in the study eye. The visual outcome for the IIH patients in our study was predominantly favourable, but patients with high-grade papilloedema had a worse visual prognosis and required more aggressive treatment.","PeriodicalId":19257,"journal":{"name":"Neuro-Ophthalmology","volume":"91 1","pages":"80 - 84"},"PeriodicalIF":0.8000,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Course and Predictors of Visual Outcome of Idiopathic Intracranial Hypertension\",\"authors\":\"R. Behbehani, Abdullah Ali, Ashraf Al-Moosa\",\"doi\":\"10.1080/01658107.2021.1984540\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ABSTRACT Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. There are few studies in the literature about the visual outcome of IIH. We have reviewed the record of 76 patients with IIH according to the modified Dandy criteria. There was a significant improvement in the Humphrey 24-2 mean deviation (MD) in the study eyes (worse affected eye at presentation) in both the medically treated group (+2.0 dB; from −5.60 dB at baseline to −3.60 dB at final follow-up, p < .01) and in the fellow eyes in the medically treated group (+1.70 dB, from −4.40 dB at baseline to −2.74 dB at final follow-up, p < .01). Higher papilloedema grade (beta −0.66, p < .001) and age (p < .02) were inversely correlated with the final visual field MD in the study eye. The visual outcome for the IIH patients in our study was predominantly favourable, but patients with high-grade papilloedema had a worse visual prognosis and required more aggressive treatment.\",\"PeriodicalId\":19257,\"journal\":{\"name\":\"Neuro-Ophthalmology\",\"volume\":\"91 1\",\"pages\":\"80 - 84\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2021-10-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuro-Ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/01658107.2021.1984540\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuro-Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/01658107.2021.1984540","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 1

摘要

特发性颅内高压(IIH)是一种以头痛和乳头状水肿为特征的临床综合征，可导致严重的视觉疾病。目前文献中关于IIH术后视觉效果的研究较少。我们根据修改后的Dandy标准回顾了76例IIH患者的记录。两种药物治疗组的研究眼(出现时受影响更严重的眼)的Humphrey 24-2平均偏差(MD)均有显著改善(+2.0 dB;从基线时的- 5.60 dB到末次随访时的- 3.60 dB, p < 0.01)，药物治疗组的同眼(+1.70 dB，从基线时的- 4.40 dB到末次随访时的- 2.74 dB, p < 0.01)。较高的乳头水肿等级(β - 0.66, p < 0.001)和年龄(p < 0.02)与研究眼的最终视野MD呈负相关。在我们的研究中，IIH患者的视力结果主要是有利的，但高度乳头状水肿患者的视力预后较差，需要更积极的治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Course and Predictors of Visual Outcome of Idiopathic Intracranial Hypertension

ABSTRACT Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. There are few studies in the literature about the visual outcome of IIH. We have reviewed the record of 76 patients with IIH according to the modified Dandy criteria. There was a significant improvement in the Humphrey 24-2 mean deviation (MD) in the study eyes (worse affected eye at presentation) in both the medically treated group (+2.0 dB; from −5.60 dB at baseline to −3.60 dB at final follow-up, p < .01) and in the fellow eyes in the medically treated group (+1.70 dB, from −4.40 dB at baseline to −2.74 dB at final follow-up, p < .01). Higher papilloedema grade (beta −0.66, p < .001) and age (p < .02) were inversely correlated with the final visual field MD in the study eye. The visual outcome for the IIH patients in our study was predominantly favourable, but patients with high-grade papilloedema had a worse visual prognosis and required more aggressive treatment.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Neuro-Ophthalmology 医学-临床神经学

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Neuro-Ophthalmology publishes original papers on diagnostic methods in neuro-ophthalmology such as perimetry, neuro-imaging and electro-physiology; on the visual system such as the retina, ocular motor system and the pupil; on neuro-ophthalmic aspects of the orbit; and on related fields such as migraine and ocular manifestations of neurological diseases.