结构碱基描述符模拟β受体阻滞剂药物的毒性

Q3 Biochemistry, Genetics and Molecular Biology

Turkish Computational and Theoretical Chemistry Pub Date : 2023-01-01 DOI:10.33435/tcandtc.1196259

Akshay Ti̇wari̇

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引用次数: 0

摘要

QSAR研究已经对35种β受体阻滞剂药物进行了毒性(Ld50)建模，使用拓扑指数。逐步多元线性回归分析方法用于建模，并通过各种类型的交叉验证参数对所获得的模型进行了严格的讨论和检验

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Mimic toxicity of Beta-blocker drugs by structural base descriptors

QSAR study has been carried out on the set of 35 Beta-blocker drugs for the modelling of toxicity (Ld50), using topological indices. The stepwise multilinear regression analysis method is used for modelling and the obtained models are critically discussed and examined by various types of cross validation parameters

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来源期刊

Turkish Computational and Theoretical Chemistry Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (miscellaneous)

CiteScore

2.40

自引率

0.00%

发文量