COVID-19恢复期患者对SARS-COV-2包膜(E)蛋白表现出体液免疫

Journal Biomed Pub Date : 2022-10-17 DOI:10.33647/2074-5982-18-3-32-36

E. Orlova, I. Kondratov, O. Ogarkov

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引用次数: 0

摘要

在这项工作中，我们获得了重组sars - cov - 2e蛋白的生产者，并开发了一个以可溶性形式表达和纯化其的系统。ELISA法证实其具有抗原性。新冠肺炎恢复期患者抗E蛋白IgG水平较对照组明显升高。

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COVID-19 Convalescents Exhibit Humoral Immunity to SARS-COV-2 Envelope (E) Protein

In this work, we obtain a producer of the recombinant SARS-CoV-2 E protein and develop a system for its expression and purification in a soluble form. ELISA confirmed its antigenic properties. In COVID-19 convalescents, the level of IgG against the E protein was significantly increased in comparison with the control group of patients.

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Journal Biomed

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