Rita A. Depprich , Jörg G. Handschel , Claus U. Fritzemeier , Rainer Engers , Norbert R. Kübler
{"title":"口腔混合型疣状癌:对临床医生和病理学家的挑战","authors":"Rita A. Depprich , Jörg G. Handschel , Claus U. Fritzemeier , Rainer Engers , Norbert R. Kübler","doi":"10.1016/j.ooe.2005.09.006","DOIUrl":null,"url":null,"abstract":"<div><p>Verrucous carcinoma (VC) a low-grade variant of squamous cell carcinoma (SCC) with specific clinical, morphologic and cytokinetic features is amongst the rarest of all oral cancers. A hybrid VC is a non-verrucous SCC that arises synchronously with the VC. We report a case of a monstrous exophytic tumor in the oral cavity. Histologic examination revealed distinct discrepancy to clinical observation. After review of the literature pathogenesis, histopathology and therapeutic options are discussed. The differential diagnosis of VC remains difficult and requires clinical and pathologic data confrontation. As the malignant behaviour of hybrid VC is confined to the non-VC component, careful examination of these tumors is recommended.</p></div>","PeriodicalId":100990,"journal":{"name":"Oral Oncology Extra","volume":"42 2","pages":"Pages 85-90"},"PeriodicalIF":0.0000,"publicationDate":"2006-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ooe.2005.09.006","citationCount":"31","resultStr":"{\"title\":\"Hybrid verrucous carcinoma of the oral cavity: A challenge for the clinician and the pathologist\",\"authors\":\"Rita A. Depprich , Jörg G. Handschel , Claus U. Fritzemeier , Rainer Engers , Norbert R. Kübler\",\"doi\":\"10.1016/j.ooe.2005.09.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Verrucous carcinoma (VC) a low-grade variant of squamous cell carcinoma (SCC) with specific clinical, morphologic and cytokinetic features is amongst the rarest of all oral cancers. A hybrid VC is a non-verrucous SCC that arises synchronously with the VC. We report a case of a monstrous exophytic tumor in the oral cavity. Histologic examination revealed distinct discrepancy to clinical observation. After review of the literature pathogenesis, histopathology and therapeutic options are discussed. The differential diagnosis of VC remains difficult and requires clinical and pathologic data confrontation. As the malignant behaviour of hybrid VC is confined to the non-VC component, careful examination of these tumors is recommended.</p></div>\",\"PeriodicalId\":100990,\"journal\":{\"name\":\"Oral Oncology Extra\",\"volume\":\"42 2\",\"pages\":\"Pages 85-90\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.ooe.2005.09.006\",\"citationCount\":\"31\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oral Oncology Extra\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1741940905000853\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral Oncology Extra","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1741940905000853","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hybrid verrucous carcinoma of the oral cavity: A challenge for the clinician and the pathologist
Verrucous carcinoma (VC) a low-grade variant of squamous cell carcinoma (SCC) with specific clinical, morphologic and cytokinetic features is amongst the rarest of all oral cancers. A hybrid VC is a non-verrucous SCC that arises synchronously with the VC. We report a case of a monstrous exophytic tumor in the oral cavity. Histologic examination revealed distinct discrepancy to clinical observation. After review of the literature pathogenesis, histopathology and therapeutic options are discussed. The differential diagnosis of VC remains difficult and requires clinical and pathologic data confrontation. As the malignant behaviour of hybrid VC is confined to the non-VC component, careful examination of these tumors is recommended.
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