基于EPID测量的SARS-COVID患者放疗剂量估算

Q4 Medicine
Nowotwory Pub Date : 2022-01-01 DOI:10.5603/NJO.a2022.0013
K. Slosarek, T. Rutkowski, Adam Gądek, Łukasz Sroka, Ł. Dolla, R. Rutkowski, J. Jaroszewicz
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引用次数: 0

摘要

介绍。由于该疾病的传染性,COVID放射治疗需要在一次现场访问期间执行所有放射治疗(RT)程序。本研究的目的是发展在治疗过程中基于电子门静脉图像装置(EPID)信号估计递送剂量的方法。材料和方法。测量电子门静脉成像装置信号作为幻体剂量的函数。估计14例COVID患者的剂量为两束X6MV。结果。该方法可在不确定度为12%的情况下对虚影剂量进行估计。在本例中,报告了一个系统错误。因此,计算临床数据的系数并用于确定患者的剂量。14例患者的计算剂量与测量剂量的平均差异为1%,但该方法的不确定度估计为±6%。该方法可作为体内法应用于临床实践。然而,由于不确定性高,它应该专门用于“大”误差的检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dose estimation in patients treated with radiotherapy for SARS-COVID disease based on EPID measurement
Introduction. COVID radiotherapy requires performance of all radiotherapy (RT) procedures during one site visit due to the infectious nature of the disease. The aim of the study was to develop methods of estimating the delivered dose based on electronic portal image device (EPID) signal during treatment. Material and methods. Electronic portal image device signal was measured as a function of the phantom dose. The dose in 14 COVID patients was estimated for two X6MV beams. Results. The method allows to estimate dose in phantom with uncertainty of 12%. In this case, a systematic error was reported. Therefore, coefficients for clinical data were calculated and used to determine the dose in patients. The mean difference between the dose calculated and the dose measured for the 14 patients was 1%, but the uncertainty of this method was estimated as ±6% Conclusions. The proposed method may be useful in clinical practice as in vivo method. However, due to high uncertainty, it should be dedicated to the detection of “big” errors.
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来源期刊
Nowotwory
Nowotwory Medicine-Oncology
CiteScore
0.90
自引率
0.00%
发文量
44
期刊介绍: NOWOTWORY Journal of Oncology publishes papers which cover all aspects of oncology but concentrates on clinical studies, both research orientated and treatment orientated, rather than on laboratory studies. Contributions are also welcomed from the fields of epidemiology, tumor pathology, radiobiology and radiation physics.
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