CRISPR技术-临床牙科的新视野-综述

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL

Bangladesh Journal of Medical Science Pub Date : 2023-05-21 DOI:10.3329/bjms.v22i20.66305

Arnab Bhattacharyya, H. Kumar, P. Mishra, Abikshyeet Panda, K. Dash, Tamanna Adhikary

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引用次数: 0

摘要

聚集规则间隔回文重复序列被称为CRISPR。它是一种蛋白质，可以通过编程来改变、消除或激活基因组。这项尖端技术提供了广泛的可能实施范围，并准备在未来几年彻底改变口腔保健。最广泛使用的基因组编辑技术包括归巢内切酶、转录激活因子样效应核酸酶、锌指核酸酶和CRISPR- CRISPR相关蛋白9 (Cas9)。这些适应性强的基因组编辑工具可以以特定序列的方式改变基因组。基因组编辑方法CRISPR-Cas9因其高效和准确，作为对抗癌症的有力武器而备受关注。本文就该方法及其在牙科领域的应用作一综述。《孟加拉国医学科学杂志》第22卷(特刊)2023年，第42-46页

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CRISPR Technology- A New Horizon in Clinical Dentistry- A Review

Clustered Regularly InterSpaced Palindromic Repeats is known as CRISPR. It is a protein that can be programmed to change, eliminate, or activate the genome. This cutting-edge technology offers a broad range of possible implementation and is poised to revolutionise oral healthcare in the years to come. The most widely utilised genome editing techniques include homing endonucleases, Transcription Activator-Like Effector Nucleases, Zinc-Finger Nucleases, and CRISPR- CRISPR-associated protein 9 (Cas9). These adaptable genome-editing tools can alter the genomes in ways that are sequence-specific. Because it is highly effective and accurate, the genome editing method CRISPR-Cas9 has drawn attention as a potent weapon in the fight against cancer. This method and its uses, particularly in dental field, are covered in this review. Bangladesh Journal of Medical Science Vol.22 (Special Issue) 2023 p.42-46

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