白色念珠菌对严重特应性皮炎敏感的变应原免疫治疗成功一例报告

F. Azad, P. Payandeh, P. Layegh, Javad Fadaee
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引用次数: 1

摘要

简介:特应性皮炎(AD)是一种炎症性、慢性、复发性、瘙痒性皮肤疾病,具有免疫学基础。这种疾病与皮肤发痒(瘙痒)、皮肤干燥(干燥)和湿疹斑块有关。空气过敏原的作用,如屋尘螨(HDM)和食物过敏原已被证明会加剧皮肤湿疹病变。除了皮质类固醇、局部润肤剂、抗组胺药、他克莫司和免疫抑制剂等药物外,还进行了光疗和皮下免疫疗法(SCIT)。SCIT主要用于致敏螨过敏原。病例介绍:我们提出了一个30岁的伊朗妇女严重特应性皮炎和致敏的念珠菌过敏原。我们用念珠菌过敏原开始SCIT,患者在开始SCIT 3个月后症状和体征有明显改善。结论:虽然皮下免疫治疗仅被批准用于螨致敏治疗特应性皮炎,但在其他气敏原致敏治疗中应考虑皮下免疫治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Case Report of a Successful Allergen Immunotherapy with Candida Albicans in Patient with Sever Atopic Dermatitis Sensitive to Candida Albicans
Introduction: Atopic dermatitis (AD) is an inflammatory, chronic, relapsing, itchy skin disease with an immunologic basis. This disease is associated with itchy skin lesions (pruritus), dry skin (xerosis) and plaques of eczema. The role of aeroallergens, such as house dust mite (HDM) and food allergens has been proven to exacerbate skin eczema lesions. Alongside drugs such as corticosteroids, topical emollients, antihistamines, tacrolimus, and immune suppressants, phototherapy and subcutaneous immunotherapy (SCIT) also done. SCIT is mostly using for sensitization to mite allergens.Case Presentation: We present a 30 y/o Iranian woman with severe atopic dermatitis and sensitization to Candida allergens. We initiated SCIT with candida allergen and the patient had obvious improvements in her signs and symptoms 3 months after starting SCIT.Conclusion: Although subcutaneous immunotherapy was only approved for mite sensitization in atopic dermatitis, it should be considered in other aeroallergen sensitizations.
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