儿童体重与气道阻塞客观指标的关系

R. Hasan, W. Abuhammour, G. Zureikat
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引用次数: 1

摘要

目的:本研究的目的是描述肥胖(体重指数第95百分位数)对肺量测定法确定的气道阻塞的客观测量的影响。设计:前瞻性横断面研究。方法:选取两所中学的226名儿童(年龄:13.6±1.5岁)。测量站立高度和熊脚体重,计算体重指数(BMI)。肺活量测定按照美国胸科学会指南进行。可逆性气道阻塞的定义基于以下标准:一秒钟用力呼气量(FEV1)比年龄和性别预测低5%。结果:226名儿童(76%)是非裔美国人,71名儿童(24%)是白人。138名(46%)儿童肥胖。36/296(12%)患儿符合可逆性气道阻塞标准,其中29/296(9.7%)患儿为肥胖。肥胖儿童的FEV1预测基线值(88±6比84±7%,p = 0.03)、FEV1 /FVC(94±6比86±8,p < 0.001)和沙丁醇治疗后FEV1预测值(95±7比88±7%,p = 0.03)均较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Relationship Between Body Weight and Objective Measures of AirwayObstruction in Children
Objective: The purpose of this study was to describe the effects of obesity (body mass index  95 th percentile) on objective measures of airway obstruction as determined by spirometry. Design: Prospective cross-sectional study. Methods: Two hundred ninty six (Age: 13.6 ± 1.5 Years) children from two middle schools were enrolled. The standing heights and weights in bear-feet were measured, and body mass index (BMI) was calculated. Spirometry was performed according to the American Thoracic Society guidelines. The definition of reversible airway obstruction was based on the following criteria: forced expiratory volume in one second (FEV1) 5% lower than predicted for age and sex. Results: Two-hundred-twenty-six children (76%) were African-American and 71 children (24%) were white. 138 (46%) children were obese. 36/296 (12%) children met the criteria for reversible airway obstruction, of which 29/296 (9.7%) were obese. Baseline FEV1 percent predicted (88 ± 6 vs 84 ± 7 %, p = 0.03), FEV1 /FVC(94 ± 6 vs 86 ± 8, p < 0.001), and FEV1 percent predicted following albuterol administration (95 ± 7 vs 88 ± 7 %, p = 0.03) were all lower in children who were obese.
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