巴氏涂片图像重叠细胞边缘检测预处理方法的优化

Q3 Decision Sciences
Nita Merlina, E. Noersasongko, P. Andono, M. Soeleman, D. Riana
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引用次数: 0

摘要

细胞结构的复杂性和高重叠导致图像对比度差。复杂的成像因素会使自动视觉判读更加困难。分割将数字图像分割成具有同质属性的不同部分,使不同区域具有不同的特征。在巴氏涂片(PS)图像上进行细胞核分割所面临的挑战是对比度差、中性粒细胞的存在以及重叠细胞染色不均匀。本研究旨在提高图像质量,准确识别细胞核。使用的方法是多项式对比度增强(PCE)模型作为预处理方法。该方法的作用是改变巴氏涂片图像与重叠细胞的对比度,使其成为检测细胞核物体边缘的重要对比度。检测过程采用Robert and Prewitt边缘检测方法,对Nusa Mandiri大学(RepomedUNM)的797张PS Repository图像进行了核目标识别测试。准确度为86.8%。比较Robert的边缘检测和Prewitt的边缘检测表明,PCE方法作为一种滤波方法可以克服颜色对比度问题,检测更准确。解决了从PS图像中检测细胞核与重叠细胞的困难。该方法可以在测试过程中将重叠的细胞与核心细胞区分开来,为提高细胞识别精度和测试更大的数据集提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimization of the Preprocessing Method for Edge Detection on Overlapping Cells at PAP Smear Images
The complexity of the cell structure and high overlap cause poor image contrast. Complex imaging factors can make automatic visual interpretation more difficult. Segmentation separates a digital image into different parts with homogeneous attributes so that different areas have different features. The challenges faced in performing nucleus segmentation on Pap Smear (PS) images are poor contrast, the presence of neutrophils, and uneven staining of overlapping cells. This research was conducted to improve image quality in identifying the nucleus accurately. The method used is the Polynomial Contrast Enhancement (PCE) model as an approach to preprocessing. This method functions to change the contrast of the Pap smear image against the overlapping cells so that it becomes a significant contrast in detecting the edge of the nucleus object. The detection process uses the Robert and Prewitt edge detection method to test the identification of the nucleus object on 797 PS Repository images of the University of Nusa Mandiri (RepomedUNM). The accuracy result obtained is 86.8%. Comparing Robert's edge detection and Prewitt's edge detection shows that the PCE approach as a filter method can overcome color contrast problems and detect more accurately. The difficulty in detecting the nucleus from the PS image against the overlapping cells can be solved. This method can distinguish overlapping cells from their core during testing, thus becoming a reference in identifying cells with improved accuracy and testing larger data sets.
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来源期刊
JOIV International Journal on Informatics Visualization
JOIV International Journal on Informatics Visualization Decision Sciences-Information Systems and Management
CiteScore
1.40
自引率
0.00%
发文量
100
审稿时长
16 weeks
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