转基因棉籽对Wistar大鼠90天重复剂量口服毒性研究

Priya Singh
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引用次数: 2

摘要

转基因种子是一种动力试验项目。它被用于90天的重复口服毒性研究。本品给wistar大鼠口服90天。本研究还比较了转基因棉籽与非转基因棉籽在最高测试温度下的性状特征。该研究的目的是产生有关主要全身毒性作用(如果有的话)、靶器官和无观察到的效应水平(NOEL) /无观察到的不良反应水平(NOAEL)的估计,以及停止使用测试项目治疗后观察到的变化(如果有的话)的可逆性的信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
90 Day Repeat DOSE Oral Toxicity Study of GM Derived Cotton Seed In Wistar Rats
GM derived seed is one type of powered test item. It is used in 90 day repeat oral toxicity studies. Powered is administered orally to wistar rats for a period of 90 days. This study also compared the profile of the GM derived cotton seed with the non GM derived cotton seed at the highest does tested. The study was performed to generate information on major systemic toxic effects (if any), target organs and an estimate of the No Observed Effect Level (NOEL) / No Observed Adverse Effect Level (NOAEL) and also reversibility of observed changes, if any, after discontinuation of treatment with the Test Items.
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