喀拉拉邦北部接种疫苗的牙科学生社区的COVID - 19突破性感染-基于调查的分析

Shalini Nair, Shahnaz Mehaboob, Shereefa Faresh, Hari S. Pillai, Vinodh Kumar, Monicah Roy
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引用次数: 4

摘要

新型冠状病毒肺炎(COVID-19)全球大流行在全球范围内感染了数亿人,给包括牙科界在内的全球医疗保健系统带来了巨大的负担。COVID-19疫苗是目前对抗迅速演变的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)的最佳防御手段。然而,对疫苗突破感染的担忧正在出现。本研究旨在评估北喀拉拉邦接种疫苗的牙科学生社区中COVID-19的突破性感染情况,并评估和比较接种疫苗和未接种疫苗的个体中COVID-19感染的严重程度。在包括BDS学生、住院外科医生和研究生在内的牙科学生社区中进行了一项调查,通过谷歌表格在线进行问卷调查,包括人口统计信息和评估COVID-19突破性感染严重程度的问题。采用SPSS 26版软件对数据进行分析。结果以频率,百分比和图表的形式呈现,显示了所检查变量的相互关系。在714名受访者中,男性占11.9%,女性占88.1%。大多数研究对象报告说已经接种了两剂新冠病毒疫苗,而11.5%的人只接种了一剂疫苗,1%的人根本没有接种疫苗。约13%的受试者在接种疫苗前有Covid阳性史,(14.7%)甚至在接种疫苗后仍被感染。新的冠状病毒变体正在不断进化,从而增加了传播和逃避宿主免疫反应的机会。这可能是我们研究中报告的14.7%突破性感染的原因。因此,强调需要进行未来的研究,以识别导致突破性感染患者疫苗反应不足的因素以及减轻这些因素的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COVID 19 breakthrough infections in vaccinated dental student community of North Kerala- A survey based analysis
The ongoing global COVID-19 pandemic has infected hundreds of millions of people over the world, imposing a tremendous burden on the global healthcare system including the dental community. COVID-19 vaccines are currently the best defense against the rapidly evolving severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there are emerging concerns about vaccine breakthrough infections. This study has been done to assess the COVID- 19 breakthrough infection among the vaccinated Dental student community of North Kerala and also evaluate and compare the severity of COVID-19 infection among vaccinated and non-vaccinated individuals. A survey was performed within the Dental student community which included BDS students, House surgeons and Post graduates by means of a questionnaire administered online via Google forms that consisted of demographic information and questions to assess severity of the COVID-19 breakthrough infection. The data were analyzed using the SPSS version 26 software. Result was presented in frequencies, percentages and charts showing the interrelatedness of the variables examined. Among the 714 respondents there were 11.9% males and 88.1% females. Majority of the study subjects reported to have completed two doses of Covid vaccine, while 11.5% had taken only a single dose and 1% had not been vaccinated at all. Around 13% of subjects gave history of being Covid positive before vaccination and (14.7%) got infected even after vaccination.New Covid variants are being evolved continuously, thereby increasing the chance for transmissibility and evasion of the host immune response. This could be the reason for the 14.7% breakthrough infections reported in our study. Therefore, the need for future studies to recognize factors leading to inadequate vaccine response in those with breakthrough infections and ways to mitigate them is highlighted.
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